Most Read

  1. Pneumococcal Vaccine as One of the Immunization Coverage Targets for Adulthood Vaccines: A Consensus Report of the Study Group for Adult Immunization of the Turkish Society of Clinical Microbiology and Infectious Diseases
  2. HIV Infection in Turkey: How Close Are We to the Target?
  3. Evaluation of HBeAg-Negative Chronic Hepatitis B Patients Who Had Undergone Liver Biopsy in Accordance With the Guidelines
  4. Does Hepatitis B Affect Erectile Dysfunction and Lower Urinary Tract Symptoms?
  5. Diagnosis, Treatment and Prevention of Diabetic Foot Wounds and Infections: Turkish Consensus Report
  6. When to Stop Antiviral Therapy in Chronic Hepatitis B
  7. Mycoplasma hominis and Ureaplasma urealyticum: Their Role in Urogenital System Infections and Retrospective Evaluation of Antibiotic Resistance Rates
  8. Crimean-Congo Haemorrhagic Fever: Treatment and Use of Ribavirin
  9. Modern Diagnostic Methods Used in Bacteriology: Rapid and Effective
  10. A Case of Generalized Tetanus With a Short Incubation Period
  11. Does Anti-HIV Positivity in Pregnancy Suggest the Requirement of HIV Prophylaxis for Newborn?
  12. Analysis of HIV/AIDS-Related Stigma and Discrimination in Turkey: Results of the People Living With HIV Stigma Index
  13. Potato Dextrose Agar With Rose-Bengal and Chloramphenicol: A New Culture Medium to Isolate Pathogenic Exophiala dermatitidis From the Environment

Volume 34, Issue 1

Original Article

Antimicrobial Resistance in Enterococcus faecalis and Enterococcus faecium Bacteria Isolated from Bloodstream Infections: A Single-Center Evaluation

Cem Çelik
Affiliations
  • Sivas Cumhuriyet Üniversitesi, Tıp Fakültesi, Tıbbi Mikrobiyoloji Anabilim Dalı, Sivas, Türkiye
https://orcid.org/0000-0002-7141-5874
,
Ayşe Hümeyra Taşkın-Kafa
Affiliations
  • Sivas Cumhuriyet Üniversitesi, Tıp Fakültesi, Tıbbi Mikrobiyoloji Anabilim Dalı, Sivas, Türkiye
https://orcid.org/0000-0002-7282-4928
,
Mürşit Hasbek
Affiliations
  • Sivas Cumhuriyet Üniversitesi, Tıp Fakültesi, Tıbbi Mikrobiyoloji Anabilim Dalı, Sivas, Türkiye
https://orcid.org/0000-0002-5217-8607
,
Seyit Ali Büyüktuna
Affiliations
  • Sivas Cumhuriyet Üniversitesi, Tıp Fakültesi, İnfeksiyon Hastalıkları ve Klinik Mikrobiyoloji Anabilim Dalı, Sivas, Türkiye
https://orcid.org/0000-0001-6518-7361
  • empiric treatment
  • Enterococcus faecalis
  • Enterococcus faecium

Abstract

Objective: Enterococci are an important cause of healthcare-related bloodstream infections. The present study aimed to contribute to form empirical treatment models that can be used in the treatment of Enterococcus faecalis and Enterococcus faecium bacteria isolated from bloodstream infections in our hospital by reviewing their resistance status against antibiotics, requently used in the treatment of these bacteria.

Methods: In our study, the resistance status of E. faecalis and E. faecium bacteria isolated from bloodstream infections in Sivas Cumhuriyet University, Health Services Practice and Research Hospital between January 2015 and June 2020 against ampicillin, amoxicillin, clavulanic acid, high-level gentamicin, linezolid, teicoplanin, and vancomycin was examined retrospectively. The diagnosis of healthcare-related bloodstream infections was made using the diagnostic criteria of “Centers for Diseases Control and Prevention (CDC).”

Results: A total of 227 enterococcal isolates were evaluated within the scope of our study between the specified dates. The percentage of patients with Enterococcus bacteria isolated in their blood cultures were 44.5% male, and 55.5% female. Of the isolates, 60.8% were identified as E. faecalis and 39.2%as E. faecium. High-level gentamicin resistance was found to be 25.3% in E. faecalis isolates, and no resistance was found against vancomycin, teicoplanin, and linezolid. In E. faecium isolates, while the highest resistance was observed against amoxicillin-clavulanic acid and ampicillin with 87.6%, vancomycin resistance was determined to be 3.3%. No resistance to linezolid was identified.

Conclusions: Enterococci cause life-threatening infections and there are some difficulties in the treatment. Especially since E. faecium has higher resistance against antibiotics, the agents to be chosen in the treatment of infections caused by these bacteria are limited. Therefore, the current local resistance data will be useful in developing rapid and appropriate treatment models, especially in cases when empirical treatment is required. We think that our study will contribute to the literature in this regard.

  • 37-41
  • Cem Çelik
  • [email protected]
  • 10.36519/kd.2021.07
  • July 9, 2020
  • December 1, 2020
  • April 30, 2021

  • Çelik C, Taşkın-Kafa AH, Hasbek M, Büyüktuna SA. [Antimicrobial resistance in Enterococcus faecalis and Enterococcus faecium bacteria isolated from bloodstream infections: A single-center evaluation]. Klimik Derg. 2021; 34(1): 37-41.
  • 569
  • 286
Download as PDF
  • This work is licensed under a Creative Commons Attribution-Non Commercial 4.0 International License. CC BY-NC
Volume 37, Issue 1 Volume 36, Issue 4 Volume 36, Supplement 1 Volume 36, Issue 3 Volume 36, Issue 2 Volume 36, Issue 1 Volume 35, Issue 4 Volume 35, Issue 3 Volume 35, Issue 2 Volume 35, Issue 1 Volume 34, Issue 3 Volume 34, Issue 2 Volume 34, Issue 1 Volume 33, Issue 3 Volume 33, Issue 2 Volume 33, Issue 1 Volume 32, Issue 3 Volume 32, Supplement 1 Volume 32, Supplement 2 Volume 32, Issue 2 Volume 32, Issue 1 Volume 31, Issue 3 Volume 31, Issue 2 Volume 31, Supplement 1 Volume 31, Issue 1 Volume 30, Issue 3 Volume 30, Issue 2 Volume 30, Supplement 1 Volume 30, Issue 1 Volume 29, Issue 3 Volume 29, Issue 2 Volume 29, Issue 1 Volume 28, Supplement 1 Volume 28, Issue 3 Volume 28, Issue 2 Volume 28, Issue 1 Volume 27, Supplement 1 Volume 27, Issue 3 Volume 27, Issue 2 Volume 27, Issue 1 Volume 26, Issue 3 Volume 26, Supplement 1 Volume 26, Issue 2 Volume 26, Issue 1 Volume 25, Issue 3 Volume 25, Issue 2 Volume 25, Issue 1 Volume 24, Issue 3 Volume 24, Issue 2 Volume 24, Issue 1 Volume 23, Issue 3 Volume 23, Issue 2 Volume 23, Issue 1 Volume 22, Issue 3 Volume 22, Issue 2 Volume 22, Issue 1 Volume 21, Issue 3 Volume 21, Supplement 2 Volume 21, Supplement 1 Volume 21, Issue 2 Volume 21, Issue 1 Volume 20, Issue 3 Volume 20, Supplement 2 Volume 20, Issue 2 Volume 20, Issue 1 Volume 20, Supplement 1 Volume 19, Issue 3 Volume 19, Issue 2 Volume 19, Issue 1 Volume 18, Issue 3 Volume 18, Supplement 1 Volume 18, Issue 2 Volume 18, Issue 1 Volume 17, Issue 3 Volume 17, Issue 2 Volume 17, Issue 1 Volume 16, Issue 3 Volume 16, Issue 2 Volume 16, Issue 1 Volume 1, Supplement 1 Volume 15, Issue 3 Volume 15, Issue 2 Volume 15, Issue 1 Volume 14, Issue 3 Volume 14, Issue 2 Volume 14, Issue 1 Volume 13, Issue 3 Volume 13, Issue 2 Volume 13, Supplement 1 Volume 13, Issue 1 Volume 12, Issue 3 Volume 12, Issue 2 Volume 12, Issue 1 Volume 11, Issue 3 Volume 11, Issue 2 Volume 11, Supplement 1 Volume 11, Issue 1 Volume 10, Issue 3 Volume 10, Issue 2 Volume 10, Issue 1 Volume 9, Issue 3 Volume 9, Issue 2 Volume 9, Issue 1 Volume 8, Issue 3 Volume 8, Issue 2 Volume 8, Issue 1 Volume 6, Issue 3 Volume 7, Issue 1 Volume 7, Issue 2 Volume 7, Issue 3 Volume 4, Issue 3 Volume 5, Issue 1 Volume 5, Issue 2 Volume 5, Issue 3 Volume 6, Issue 1 Volume 6, Issue 2 Volume 3, Issue 1 Volume 3, Issue 2 Volume 3, Issue 3 Volume 4, Issue 1 Volume 4, Issue 2 Volume 1, Issue 2 Volume 2, Issue 1 Volume 2, Issue 2 Volume 2, Issue 3 Volume 1, Issue 1