Objective: Hepatitis B virus (HBV) infection is a widespread health problem all over the world and has high morbidity and mortality. Erectile dysfunction (ED) is defined as the inability to obtain or maintain a penile erection sufficient for achieving satisfactory sexual activity. We evaluated the prevalence of ED and lower urinary tract symptoms in patients with hepatitis B.
Methods: Our cross-sectional study was carried out in infectious diseases and clinical microbiology and urology outpatient clinics. The study included 58 hepatitis B patients who did not receive antiviral therapy and 93 patients as a control group. The International Prostate Symptom Score (IPSS) form was used to identify lower urinary tract symptoms, and the International Index of Erectile Function (IIEF) form was used to assess sexual functions.
Results: The mean ages of patients with hepatitis B and control group were 46.55±9.18 and 43.45±12.70 years, respectively (p=0.11). When we analyzed 58 patients; 27 (46.6%) of them were chronic hepatitis B (CHB) and 31 (53.4%) of them were of inactive hepatitis B carriers. The prevalence of ED was 67.2% and 46.2% for those with hepatitis B and control group, respectively (p=0.01). When subgroup analysis was performed, ED was 81.5% and 54.8% in CHB patients and inactive carriers, respectively, and the difference between the groups was statistically significant (p=0.03). The mean IIEF was 18.33±5.45 and 20.49±4.97 (p=0.01) and the mean IPSS was 8.05± 6.99 and 5.39±6.00 in the hepatitis B patients and the control group, respectively (p=0.02).
Conclusions: In our study, it was determined that the prevalence of ED and lower urinary tract symptoms were increased in hepatitis B patients. Patients with hepatitis B should be monitored for ED and evaluated for treatment. There is a need of prospective randomized and controlled studies in this area.
Cite this article as: Asan i, Çoban S, Türkoğlu AR, Akça MÖ, Güzelsoy M. [Does hepatitis B affect erectile dysfunction and lower urinary tract symptoms?]. Klimik Derg. 2018; 31(1): 46-9. Turkish.