Most Read

  1. Pneumococcal Vaccine as One of the Immunization Coverage Targets for Adulthood Vaccines: A Consensus Report of the Study Group for Adult Immunization of the Turkish Society of Clinical Microbiology and Infectious Diseases
  2. HIV Infection in Turkey: How Close Are We to the Target?
  3. Evaluation of HBeAg-Negative Chronic Hepatitis B Patients Who Had Undergone Liver Biopsy in Accordance With the Guidelines
  4. Does Hepatitis B Affect Erectile Dysfunction and Lower Urinary Tract Symptoms?
  5. Diagnosis, Treatment and Prevention of Diabetic Foot Wounds and Infections: Turkish Consensus Report
  6. When to Stop Antiviral Therapy in Chronic Hepatitis B
  7. Mycoplasma hominis and Ureaplasma urealyticum: Their Role in Urogenital System Infections and Retrospective Evaluation of Antibiotic Resistance Rates
  8. Crimean-Congo Haemorrhagic Fever: Treatment and Use of Ribavirin
  9. Modern Diagnostic Methods Used in Bacteriology: Rapid and Effective
  10. A Case of Generalized Tetanus With a Short Incubation Period
  11. Does Anti-HIV Positivity in Pregnancy Suggest the Requirement of HIV Prophylaxis for Newborn?
  12. Analysis of HIV/AIDS-Related Stigma and Discrimination in Turkey: Results of the People Living With HIV Stigma Index
  13. Potato Dextrose Agar With Rose-Bengal and Chloramphenicol: A New Culture Medium to Isolate Pathogenic Exophiala dermatitidis From the Environment

Volume 33, Issue 3

Original Article

Anaerobic Bacteria Isolated From Blood Cultures in Hacettepe University Faculty of Medicine Hospital Between 2017 and 2019: A Three-Year Evaluation

Mervenur Demir-Çuha
Affiliations
  • Hacettepe Üniversitesi, Tıbbi Mikrobiyoloji Anabilim Dalı, Ankara, Türkiye
,
Gülşen Hazırolan
Affiliations
  • Hacettepe Üniversitesi, Tıp Fakültesi, Tıbbi Mikrobiyoloji Anabilim Dalı, Ankara, Türkiye
  • anaerobic bacteria
  • bacteremia
  • blood culture

Objective: The incidence of anaerobic bacteremia varies according to regions, health institutions, and patient population. Anaerobic bacteria are isolated from blood cultures with a frequency of 0.5-13%. The aim of this study is to determine the incidence and the distribution of anaerobic bacteria in a university hospital over a three-year period.

Methods: In this study, microbiological and demographic data of anaerobic bacteremia cases detected in our hospital between 2017 and 2019 were analyzed, retrospectively. Matrix-assisted laser desorption ionization-time of flight mass spectrometry (MALDI-TOF MS, Bruker, Daltonik, Bremen, Germany) was used to identify the isolates.

Results: Anaerobic bacteria isolated from blood cultures were Bacteroides fragilis group (n=40), Cutibacterium spp. (n=27), Gram-positive anaerobic cocci (n=17), Actinomyces spp. (n=14), Clostridium spp. (n=11), Fusobacterium spp. (n=2), Prevotella spp. (n=2) and Porphyromonas asaccharolytica, (n=1) respectively. In addition, two Gram-positive anaerobic bacilli and one Gram-negative anaerobic bacillus which could not be identified by MALDI-TOF MS were isolated. Polymicrobial anaerobic bacteremia was not detected. 53.8% of the patients were male and 46.2% were female. The median age of the patients was 64 (age range, 1-92) years and 96.6% of them were adult patients. Comorbidities were common in patients with anaerobic bacteremia, and the most common underlying diseases were solid and hematological malignancies. In our hospital, 30-day mortality rate in anaerobic bacteremia cases was 25.6%. Clostridum spp. and B. fragilis group constituted 73.3% of the cases with mortality. The 30-day mortality of the patients with bacteremia with these two species was found to be significantly higher than the other species (p=0.001).

Conclusions: In conclusion, although the incidence of anaerobic bacteremia is low, hospitals should regularly examine the prevalence of anaerobic bacteremia and its related factors due to their high mortality rates, impact of appropriate antimicrobial therapy in prognosis, and the increasing rate of resistance in anaerobic bacteria in recent years.

Klimik Dergisi 2020; 33(3): 286-91.

Cite this article as: Demir-Çuha M, Hazırolan G. [Anaerobic bacteria isolated from blood cultures in Hacettepe University Faculty of Medicine Hospital between 2017 and 2019: A three-year evaluation]. Klimik Derg. 2020; 33(3): 286-91. Turkish.

  • 286-291
  • 10.5152/kd.2020.58
  • December 31, 2020
  • 695
  • 295
Download as PDF
  • This work is licensed under a Creative Commons Attribution-Non Commercial 4.0 International License. CC BY-NC
Volume 37, Issue 1 Volume 36, Issue 4 Volume 36, Supplement 1 Volume 36, Issue 3 Volume 36, Issue 2 Volume 36, Issue 1 Volume 35, Issue 4 Volume 35, Issue 3 Volume 35, Issue 2 Volume 35, Issue 1 Volume 34, Issue 3 Volume 34, Issue 2 Volume 34, Issue 1 Volume 33, Issue 3 Volume 33, Issue 2 Volume 33, Issue 1 Volume 32, Issue 3 Volume 32, Supplement 1 Volume 32, Supplement 2 Volume 32, Issue 2 Volume 32, Issue 1 Volume 31, Issue 3 Volume 31, Issue 2 Volume 31, Supplement 1 Volume 31, Issue 1 Volume 30, Issue 3 Volume 30, Issue 2 Volume 30, Supplement 1 Volume 30, Issue 1 Volume 29, Issue 3 Volume 29, Issue 2 Volume 29, Issue 1 Volume 28, Supplement 1 Volume 28, Issue 3 Volume 28, Issue 2 Volume 28, Issue 1 Volume 27, Supplement 1 Volume 27, Issue 3 Volume 27, Issue 2 Volume 27, Issue 1 Volume 26, Issue 3 Volume 26, Supplement 1 Volume 26, Issue 2 Volume 26, Issue 1 Volume 25, Issue 3 Volume 25, Issue 2 Volume 25, Issue 1 Volume 24, Issue 3 Volume 24, Issue 2 Volume 24, Issue 1 Volume 23, Issue 3 Volume 23, Issue 2 Volume 23, Issue 1 Volume 22, Issue 3 Volume 22, Issue 2 Volume 22, Issue 1 Volume 21, Issue 3 Volume 21, Supplement 2 Volume 21, Supplement 1 Volume 21, Issue 2 Volume 21, Issue 1 Volume 20, Issue 3 Volume 20, Supplement 2 Volume 20, Issue 2 Volume 20, Issue 1 Volume 20, Supplement 1 Volume 19, Issue 3 Volume 19, Issue 2 Volume 19, Issue 1 Volume 18, Issue 3 Volume 18, Supplement 1 Volume 18, Issue 2 Volume 18, Issue 1 Volume 17, Issue 3 Volume 17, Issue 2 Volume 17, Issue 1 Volume 16, Issue 3 Volume 16, Issue 2 Volume 16, Issue 1 Volume 1, Supplement 1 Volume 15, Issue 3 Volume 15, Issue 2 Volume 15, Issue 1 Volume 14, Issue 3 Volume 14, Issue 2 Volume 14, Issue 1 Volume 13, Issue 3 Volume 13, Issue 2 Volume 13, Supplement 1 Volume 13, Issue 1 Volume 12, Issue 3 Volume 12, Issue 2 Volume 12, Issue 1 Volume 11, Issue 3 Volume 11, Issue 2 Volume 11, Supplement 1 Volume 11, Issue 1 Volume 10, Issue 3 Volume 10, Issue 2 Volume 10, Issue 1 Volume 9, Issue 3 Volume 9, Issue 2 Volume 9, Issue 1 Volume 8, Issue 3 Volume 8, Issue 2 Volume 8, Issue 1 Volume 6, Issue 3 Volume 7, Issue 1 Volume 7, Issue 2 Volume 7, Issue 3 Volume 4, Issue 3 Volume 5, Issue 1 Volume 5, Issue 2 Volume 5, Issue 3 Volume 6, Issue 1 Volume 6, Issue 2 Volume 3, Issue 1 Volume 3, Issue 2 Volume 3, Issue 3 Volume 4, Issue 1 Volume 4, Issue 2 Volume 1, Issue 2 Volume 2, Issue 1 Volume 2, Issue 2 Volume 2, Issue 3 Volume 1, Issue 1