Abstract

Invasive liver abscess syndrome caused by Klebsiella pneumoniae was first reported from Taiwan and related researches were generally conducted in Eastern Asian countries. However, in recent years similar cases are described all around the world. A minority of patients with primary liver abscess develop metastatic infection at other site of the body, but it is more prevalent when the etiologic agent is K. pneumoniae, especially K1 and K2 serotypes. The most common manifestations of metastatic infection are endophthalmitis, meningitis and brain abscess. A 49-year-old non-diabetic male who presented with primary liver abscess due to K. pneumoniae accompanied by endophthalmitis as a metastatic infection is reported to draw attention to this syndrome with high morbidity. Permanent complete vision loss occurred despite systemic and local antibiotic treatment and percutaneous drainage. Serologic subtyping and virulence analysis of the etiologic agent should be performed when this syndrome is suspected.