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Volume 31, Issue 2

Review

Bacteriophage Therapy: An Unforgetten Source of Cure

Aycan Gündoğdu
Affiliations
  • Erciyes Üniversitesi, Tıp Fakültesi, Tıbbi Mikrobiyoloji Anabilim Dalı, Kayseri, Türkiye
,
Ayşegül Ulu-Kılıç
Affiliations
  • Erciyes Üniversitesi, Tıp Fakültesi, İnfeksiyon Hastalıkları ve Klinik Mikrobiyoloji Anabilim Dalı, Kayseri, Türkiye
  • Bacteriophages
  • multiple drug resistance
  • phage therapy

Abstract

Multidrug resistance observed in microorganisms, especially in hospital-based pathogens, poses a serious public health threat. While scientists have not been able to develop a radical solution for the increasing antibiotic resistance problem, the search for treatment alternatives in appropriate clinical settings continues consistently. Although bacteriophage (phage) therapy was quite popular between 1920 and 1950, it has been abandoned in many parts of the world due to various reasons, nowadays it is again at the agenda and is at the forefront of alternative therapies. In this rediscovery process in area of infectious diseases and clinical microbiology, it is important to consider the interesting history of phage therapy, the reasons for abandonment, the advantages/disadvantages over antibiotics, and the concerns about deployment in clinical use.

Cite this article as: Gündoğdu A, Ulu-Kılıç A. [Bacteriophage therapy: An unforgetten source of cure]. Klimik Derg. 2018; 31(2): 78-87. Turkish.

  • 78-87
  • 10.5152/kd.2018.22
  • July 23, 2019
  • 3588
  • 814
Download as PDF
  • This work is licensed under a Creative Commons Attribution-Non Commercial 4.0 International License. CC BY-NC
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