Most Read

  1. Pneumococcal Vaccine as One of the Immunization Coverage Targets for Adulthood Vaccines: A Consensus Report of the Study Group for Adult Immunization of the Turkish Society of Clinical Microbiology and Infectious Diseases
  2. HIV Infection in Turkey: How Close Are We to the Target?
  3. Evaluation of HBeAg-Negative Chronic Hepatitis B Patients Who Had Undergone Liver Biopsy in Accordance With the Guidelines
  4. Does Hepatitis B Affect Erectile Dysfunction and Lower Urinary Tract Symptoms?
  5. Diagnosis, Treatment and Prevention of Diabetic Foot Wounds and Infections: Turkish Consensus Report
  6. When to Stop Antiviral Therapy in Chronic Hepatitis B
  7. Mycoplasma hominis and Ureaplasma urealyticum: Their Role in Urogenital System Infections and Retrospective Evaluation of Antibiotic Resistance Rates
  8. Crimean-Congo Haemorrhagic Fever: Treatment and Use of Ribavirin
  9. Modern Diagnostic Methods Used in Bacteriology: Rapid and Effective
  10. A Case of Generalized Tetanus With a Short Incubation Period
  11. Does Anti-HIV Positivity in Pregnancy Suggest the Requirement of HIV Prophylaxis for Newborn?
  12. Analysis of HIV/AIDS-Related Stigma and Discrimination in Turkey: Results of the People Living With HIV Stigma Index
  13. Potato Dextrose Agar With Rose-Bengal and Chloramphenicol: A New Culture Medium to Isolate Pathogenic Exophiala dermatitidis From the Environment

Volume 28, Issue 1

Original Article

Antibiotic Resistance and Investigation of IMP-1, IMP-2, VIM-1 and VIM-2 Metallo-β-Lactamases in Acinetobacter Strains Isolated From Clinical Samples

Merve Ocak
Affiliations
  • Mustafa Kemal Üniversitesi, Tayfur Ata Sökmen Tıp Fakültesi, Tıbbi Mikrobiyoloji Anabilim Dalı, Hatay, Türkiye
,
Burçin Özer
Affiliations
  • Mustafa Kemal Üniversitesi, Tayfur Ata Sökmen Tıp Fakültesi, Tıbbi Mikrobiyoloji Anabilim Dalı, Hatay, Türkiye
,
Melek İnci
Affiliations
  • Mustafa Kemal Üniversitesi, Tayfur Ata Sökmen Tıp Fakültesi, Tıbbi Mikrobiyoloji Anabilim Dalı, Hatay, Türkiye
,
Nizami Duran
Affiliations
  • Mustafa Kemal Üniversitesi, Tayfur Ata Sökmen Tıp Fakültesi, Tıbbi Mikrobiyoloji Anabilim Dalı, Hatay, Türkiye
  • Acinetobacter
  • antibiotic resistance
  • IMP1
  • IMP2
  • metalloβlactamase
  • VIM1
  • VIM2

Abstract

Objective: It was aimed to investigate the presence of metallo-β-lactamase (MBL) production and blaIMP-1, blaIMP-2, blaVIM-1 and blaVIM-2 genes in Acinetobacter strains isolated from clinical samples.

Methods: 150 Acinetobacter strains isolated from clinical samples which were sent to microbiology laboratory from March 2009 to June 2012 were included in the study. The antimicrobial susceptibilities of the strains were determined using automated system, and production of metallo-β-lactamase was investigated via Etest®. Polymerase chain reaction (PCR) method was used for determining the blaIMP-1, blaIMP-2, blaVIM-1  and blaVIM-2  genes.

Results: 94% of strains were Acinetobacter baumannii and, 6% of strains were A. lwoffii. The strains were mostly susceptible to gentamicin (41.3%), amikacin (36.7%), and imipenem (25.3%), while they were resistant to ceftriaxone (92%), levofloxacin (84.7%), ceftazidime (84%), and piperacillin-tazobactam (84%). Sixty seven (44.7%) of the strains were MBL-positive via Etest®, and these strains were detected more resistant to imipenem, meropenem, ceftazidime, and ceftriaxone. No blaIMP-1, blaIMP-2, blaVIM-1 and blaVIM-2 genes were detected.,

Conclusions: While MBL production was detected in 44.7% of Acinetobacter strains, blaIMP-1, blaIMP-2, blaVIM-1 and blaVIM-2 genes were not determined.

  • 23-27
  • 10.5152/kd.2015.05
  • July 23, 2019
  • 1904
  • 621
Download as PDF
  • This work is licensed under a Creative Commons Attribution-Non Commercial 4.0 International License. CC BY-NC
Volume 37, Issue 1 Volume 36, Issue 4 Volume 36, Supplement 1 Volume 36, Issue 3 Volume 36, Issue 2 Volume 36, Issue 1 Volume 35, Issue 4 Volume 35, Issue 3 Volume 35, Issue 2 Volume 35, Issue 1 Volume 34, Issue 3 Volume 34, Issue 2 Volume 34, Issue 1 Volume 33, Issue 3 Volume 33, Issue 2 Volume 33, Issue 1 Volume 32, Issue 3 Volume 32, Supplement 1 Volume 32, Supplement 2 Volume 32, Issue 2 Volume 32, Issue 1 Volume 31, Issue 3 Volume 31, Issue 2 Volume 31, Supplement 1 Volume 31, Issue 1 Volume 30, Issue 3 Volume 30, Issue 2 Volume 30, Supplement 1 Volume 30, Issue 1 Volume 29, Issue 3 Volume 29, Issue 2 Volume 29, Issue 1 Volume 28, Supplement 1 Volume 28, Issue 3 Volume 28, Issue 2 Volume 28, Issue 1 Volume 27, Supplement 1 Volume 27, Issue 3 Volume 27, Issue 2 Volume 27, Issue 1 Volume 26, Issue 3 Volume 26, Supplement 1 Volume 26, Issue 2 Volume 26, Issue 1 Volume 25, Issue 3 Volume 25, Issue 2 Volume 25, Issue 1 Volume 24, Issue 3 Volume 24, Issue 2 Volume 24, Issue 1 Volume 23, Issue 3 Volume 23, Issue 2 Volume 23, Issue 1 Volume 22, Issue 3 Volume 22, Issue 2 Volume 22, Issue 1 Volume 21, Issue 3 Volume 21, Supplement 2 Volume 21, Supplement 1 Volume 21, Issue 2 Volume 21, Issue 1 Volume 20, Issue 3 Volume 20, Supplement 2 Volume 20, Issue 2 Volume 20, Issue 1 Volume 20, Supplement 1 Volume 19, Issue 3 Volume 19, Issue 2 Volume 19, Issue 1 Volume 18, Issue 3 Volume 18, Supplement 1 Volume 18, Issue 2 Volume 18, Issue 1 Volume 17, Issue 3 Volume 17, Issue 2 Volume 17, Issue 1 Volume 16, Issue 3 Volume 16, Issue 2 Volume 16, Issue 1 Volume 1, Supplement 1 Volume 15, Issue 3 Volume 15, Issue 2 Volume 15, Issue 1 Volume 14, Issue 3 Volume 14, Issue 2 Volume 14, Issue 1 Volume 13, Issue 3 Volume 13, Issue 2 Volume 13, Supplement 1 Volume 13, Issue 1 Volume 12, Issue 3 Volume 12, Issue 2 Volume 12, Issue 1 Volume 11, Issue 3 Volume 11, Issue 2 Volume 11, Supplement 1 Volume 11, Issue 1 Volume 10, Issue 3 Volume 10, Issue 2 Volume 10, Issue 1 Volume 9, Issue 3 Volume 9, Issue 2 Volume 9, Issue 1 Volume 8, Issue 3 Volume 8, Issue 2 Volume 8, Issue 1 Volume 6, Issue 3 Volume 7, Issue 1 Volume 7, Issue 2 Volume 7, Issue 3 Volume 4, Issue 3 Volume 5, Issue 1 Volume 5, Issue 2 Volume 5, Issue 3 Volume 6, Issue 1 Volume 6, Issue 2 Volume 3, Issue 1 Volume 3, Issue 2 Volume 3, Issue 3 Volume 4, Issue 1 Volume 4, Issue 2 Volume 1, Issue 2 Volume 2, Issue 1 Volume 2, Issue 2 Volume 2, Issue 3 Volume 1, Issue 1