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Early Release / Consensus Report

Use of the BioFire® FilmArray® Pneumonia Plus Rapid Syndromic Multiplex PCR Assay in Pneumonia Patients – An Expert Opinion Report

Elif Demirören-Çayırcı and Others

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Volume 38, Issue 3

Early Release / Consensus Report

Use of the BioFire® FilmArray® Pneumonia Plus Rapid Syndromic Multiplex PCR Assay in Pneumonia Patients – An Expert Opinion Report

Elif Demirören-Çayırcı
Affiliations
  • Türkiye bioMérieux, Medikal İlişkiler Bölümü, İstanbul, Türkiye
https://orcid.org/0009-0002-2951-987X
,
Candan Çiçek
Affiliations
  • Ege Üniversitesi Tıp Fakültesi, Tıbbi Mikrobiyoloji Anabilim Dalı, İzmir, Türkiye
https://orcid.org/0000-0002-3486-8305
,
Zeynep Ceren Karahan
Affiliations
  • Ankara Üniversitesi Tıp Fakültesi, Tıbbi Mikrobiyoloji Anabilim Dalı, Ankara, Türkiye
https://orcid.org/0000-0001-7727-3363
,
Tuğhan Utku
Affiliations
  • Yeditepe Üniversitesi Tıp Fakültesi, Anestezi ve Reanimasyon Anabilim Dalı, İstanbul, Türkiye
https://orcid.org/0000-0002-2226-4694
,
Önder Ergönül
Affiliations
  • Koç Üniversitesi Tıp Fakültesi, İnfeksiyon Hastalıkları ve Klinik Mikrobiyoloji Anabilim Dalı, İstanbul, Türkiye
https://orcid.org/0000-0003-1935-9235
,
Nimet Şenoğlu
Affiliations
  • Bakırçay Üniversitesi Tıp Fakültesi Çiğli Eğitim ve Araştırma Hastanesi, Anestezi ve Reanimasyon Kliniği, İzmir, Türkiye
https://orcid.org/0000-0001-9932-9401
,
İlker Devrim
Affiliations
  • Sağlık Bilimleri Üniversitesi Dr. Behçet Uz Çocuk Hastalıkları ve Cerrahisi Eğitim ve Araştırma Hastanesi, Çocuk İnfeksiyon Hastalıkları Kliniği, İzmir, Türkiye
https://orcid.org/0000-0002-6053-8027
,
Begüm Ergan
Affiliations
  • Dokuz Eylül Üniversitesi Tıp Fakültesi, Göğüs Hastalıkları Anabilim Dalı, İzmir, Türkiye
https://orcid.org/0000-0003-2920-9214
,
Murat Akova
Affiliations
  • Hacettepe Üniversitesi Tıp Fakültesi, İnfeksiyon Hastalıkları ve Klinik Mikrobiyoloji Anabilim Dalı, Ankara, Türkiye
https://orcid.org/0000-0002-6904-9473
  • antimicrobial stewardship
  • molecular diagnostic techniques
  • pneumonia

Abstract

This consensus report presents current expert opinions on the clinical use of the BioFire® FilmArray® Pneumonia Plus (PNplus) rapid molecular test in patients with pneumonia. A group of eight physicians with clinical experience in pneumonia identified common questions encountered in clinical practice regarding the use of PNplus for lower respiratory tract infections and developed consensus-based answers. Based on this process, a list of recommendations was compiled for the use of the PNplus rapid syndromic molecular test, which detects the most common bacteria, viruses, and resistance genes. These recommendations were supported by case examples based on fictional clinical scenarios, along with a proposed diagnostic algorithm for the management of pneumonia.

Show References

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  • Demirören-Çayırcı E, Çiçek C, Karahan ZC, et al. [Use of the BioFire® FilmArray® Pneumonia Plus Rapid Syndromic Multiplex PCR Assay in pneumonia patients – An expert opinion report ]. Klimik Derg. 2025;38(4). Turkish.
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