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Volume 29, Issue 3

Case Report

Acute Generalized Exanthematous Pustulosis Due to Pyrazinamide in a Patient Receiving Antituberculous Treatment: A Case Report

Rezan Harman
Affiliations
  • Özel Sani Konukoğlu Hastanesi, İnfeksiyon Hastalıkları ve Klinik Mikrobiyoloji Kliniği, Gaziantep, Türkiye
,
Elif Yıldırım
Affiliations
  • Sanko Üniversitesi, Tıp Fakültesi, Deri ve Zührevi Hastalıklar Anabilim Dalı, Gaziantep, Türkiye
,
Özgür Günal
Affiliations
  • Sağlık Bilimleri Üniversitesi, Samsun Eğitim ve Araştırma Hastanesi, İnfeksiyon Hastalıkları ve Klinik Mikrobiyoloji Kliniği, Samsun, Türkiye
,
Arzu Didem Yalçın
Affiliations
  • Sağlık Bilimleri Üniversitesi, Antalya Eğitim ve Araştırma Hastanesi, İmmünoloji ve Alerji Hastalıkları Kliniği, Antalya, Türkiye
,
Mustafa Namıduru
Affiliations
  • Gaziantep Üniversitesi, Tıp Fakültesi, İnfeksiyon Hastalıkları ve Klinik Mikrobiyoloji Anabilim Dalı, Gaziantep, Türkiye
,
Mehmet Sökücü
Affiliations
  • Sanko Üniversitesi, Tıbbi Patoloji Anabilim Dalı, Gaziantep, Türkiye
,
Can Polat Eyigün
Affiliations
  • Sanko Üniversitesi, Tıp Fakültesi, İnfeksiyon Hastalıkları ve Klinik Mikrobiyoloji Anabilim Dalı, Gaziantep, Türkiye
  • Acute generalized exanthematous pustulosis
  • Tuberculous meningitis

Abstract

Acute generalized exanthematous pustulosis (AGEP) is a rare cutaneous eruption characterized by generalized non-follicular sterile pustules. The most frequent causes are antibiotics, sulphonamides, and antipyretic analgesics. It is rarely reported to occur due to antituberculous medications. We present here a 27-year-old patient in whom AGEP developed 3 times after the same treatment while receiving a combination of isoniazid, rifampin, ethambutol and pyrazinamide for tuberculous meningitis, in whom the causative drug was found to be pyrazinamide.

  • 133-135
  • 10.5152/kd.2016.32
  • July 23, 2019
  • 2679
  • 967
Download as PDF
  • This work is licensed under a Creative Commons Attribution-Non Commercial 4.0 International License. CC BY-NC
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