{"id":26654,"date":"2023-03-21T13:26:13","date_gmt":"2023-03-21T10:26:13","guid":{"rendered":"https:\/\/www.klimikdergisi.org\/?p=26654"},"modified":"2023-03-21T14:23:50","modified_gmt":"2023-03-21T11:23:50","slug":"hhv-8-yayinlarinin-bibliyometrik-analizi","status":"publish","type":"post","link":"https:\/\/www.klimikdergisi.org\/tr\/2023\/03\/21\/hhv-8-yayinlarinin-bibliyometrik-analizi\/","title":{"rendered":"T\u00fcrkiye\u2019deki HIV\/AIDS ile \u0130li\u015fkili HHV-8\/KSHV Yay\u0131nlar\u0131n\u0131n Bibliyometrik Analizi: 2001-2020"},"content":{"rendered":"

G\u0130R\u0130\u015e<\/h2>\n

\u0130nsan herpes virusu 8 (human herpes virus 8-HHV-8) veya di\u011fer ad\u0131yla Kaposi sarkomu herpes virusu (KSHV), Rhadinovirus<\/i> cinsine ait gamma herpes virus ailesindendir. Kan ve kan \u00fcr\u00fcnleri, organ nakli, t\u00fck\u00fcr\u00fck ve cinsel temasla bula\u015fabilmekte ve lenfoid dokularda latent olarak kalmaktad\u0131r (1). \u0130mm\u00fcns\u00fcpresif hastalar\u0131n t\u00fck\u00fcr\u00fck ve oral mukozas\u0131nda bulunabilen HHV-8 virusu onkojenik bir virus olup Kaposi sarkomu (KS) ve lenfoproliferatif hastal\u0131klar\u0131n etiyolojisinde \u00f6nemli bir yere sahiptir (2).<\/p>\n

Kaposi sarkomu, 1980 y\u0131l\u0131 \u00f6ncesinde nadiren g\u00f6r\u00fclen bir vask\u00fcler malignitedir ve o y\u0131llarda klasik, endemik ve iatrojenik olarak bilinen \u00fc\u00e7 tipi mevcuttur. HIV\/AIDS pandemisi ile birlikte \u00f6zellikle homoseks\u00fcel erkekler aras\u0131nda KS olgular\u0131nda dramatik bir art\u0131\u015f g\u00f6r\u00fclm\u00fc\u015ft\u00fcr; hatta KS k\u0131sa bir s\u00fcre sonra \u201chuman immunodeficiency virus\u201d infeksiyonu ve \u201cacquired immunodeficiency syndrome\u201d (HIV\/AIDS) olgular\u0131nda klinik bir belirte\u00e7 olarak tan\u0131mlanm\u0131\u015f ve epidemik KS (HIV ili\u015fkili KS) olarak adland\u0131r\u0131lm\u0131\u015ft\u0131r (3,4). \u0130nsan herpes virusu 8\u2019in HIV ve KS ile ili\u015fkisi ilk kez 1994 y\u0131l\u0131nda AIDS tan\u0131l\u0131 bir hastan\u0131n doku biyopsisinde tespit edilmi\u015f ve HHV-8\u2019in KS etiyolojisindeki yerinin \u00f6nemi bu \u015fekilde anla\u015f\u0131lm\u0131\u015ft\u0131r (5).<\/p>\n

\u00dclkelere ve co\u011frafi b\u00f6lgelere g\u00f6re HHV-8\/KSHV prevalans\u0131nda farkl\u0131l\u0131klar g\u00f6r\u00fclmektedir; Amerika\u2019da %1-5, baz\u0131 Akdeniz \u00fclkelerinde %10-20 ve Sahra alt\u0131 Afrika\u2019n\u0131n baz\u0131 b\u00f6lgelerinde ise %30-%80 aras\u0131ndad\u0131r (5). Epidemik KS hastalar\u0131nda ise HHV-8 insidans\u0131n\u0131n %50-60\u2019lara kadar y\u00fckseldi\u011fi g\u00f6r\u00fclmektedir (6). Son 20 y\u0131ll\u0131k s\u00fcre\u00e7te geli\u015ftirilen antiretroviral tedaviler HIV hastalar\u0131n\u0131n ba\u011f\u0131\u015f\u0131kl\u0131\u011f\u0131nda iyile\u015fme sa\u011flam\u0131\u015f olup HIV RNA\u2019n\u0131n h\u0131zla saptanamaz d\u00fczeye gelmesiyle KS olgu say\u0131lar\u0131nda azalma ya\u015fanm\u0131\u015ft\u0131r (7). Buna ra\u011fmen KS g\u00fcn\u00fcm\u00fczde halen HIV ile ya\u015fayan bireylerde en s\u0131k g\u00f6r\u00fclen malignitelerden biri olmaya ve \u00f6nemini korumaya devam etmektedir (8). Yap\u0131lan literat\u00fcr taramas\u0131nda, \u00fclkemizde HIV ile infekte birey ve AIDS olgu say\u0131lar\u0131nda y\u0131llar i\u00e7inde h\u0131zl\u0131 bir art\u0131\u015f olmas\u0131na ra\u011fmen HHV-8 ili\u015fkili KS kapsam\u0131nda yap\u0131lm\u0131\u015f az say\u0131da \u00e7al\u0131\u015fma oldu\u011fu g\u00f6r\u00fcld\u00fc ve bu konuda yap\u0131lm\u0131\u015f bibliyometrik bir \u00e7al\u0131\u015fmaya da rastlanmad\u0131.<\/p>\n

Bibliyometrik analiz, \u00e7ok say\u0131da ara\u015ft\u0131rmadan elde edilen bilimsel veriyi ara\u015ft\u0131rmak ve analiz etmek i\u00e7in kullan\u0131lan bir y\u00f6ntemdir. Bibliyometrik analizler, makale ve dergilerin performans \u00f6l\u00e7\u00fcmlerinde, i\u015f birli\u011fi modellerinde ve ara\u015ft\u0131rma bile\u015fenlerinde ortaya \u00e7\u0131kan e\u011filimleri g\u00f6rmek ve mevcut literat\u00fcrde belirli bir alan\u0131n entelekt\u00fcel yap\u0131s\u0131n\u0131 anlamak i\u00e7in yap\u0131lan \u00e7al\u0131\u015fmalarda yayg\u0131n olarak kullan\u0131lmaktad\u0131r. S\u00f6z konusu analizler, belirli bir bilimsel konunun \u201cevrimsel\u201d s\u00fcrecinin ortaya konulmas\u0131n\u0131n yan\u0131 s\u0131ra ortaya \u00e7\u0131kan verilerle farkl\u0131 alanlara \u0131\u015f\u0131k tutulmas\u0131n\u0131 da sa\u011flar (9,10).<\/p>\n

\u00c7al\u0131\u015fmam\u0131z kapsam\u0131nda \u00fclkemizdeki HIV\/AIDS ile ili\u015fkili HHV-8\/KSHV infeksiyonu literat\u00fcr\u00fcn\u00fcn bibliyometrik analizini yapmay\u0131 ama\u00e7lad\u0131k.<\/p>\n

Y\u00d6NTEMLER<\/h2>\n

Bibliyometrik analizler kapsam\u0131nda verileri taramak i\u00e7in \u00e7e\u015fitli elektronik veritabanlar\u0131 kullan\u0131labilir. \u00c7al\u0131\u015fmam\u0131zda k\u00fcresel bir bilgi analiz \u015firketi olan Elsevier taraf\u0131ndan geli\u015ftirilen Scopus veritaban\u0131 kullan\u0131ld\u0131. S\u00f6z konusu veritaban\u0131, Clarivate Analytics\u2019in \u201cWeb of Science -(WoS)\u201d ve ABD Ulusal T\u0131p K\u00fct\u00fcphanesi\u2019nin \u00fccretsiz biyomedikal veritaban\u0131\u00a0 <\/span>PubMed\u2019in \u00f6zelliklerini birle\u015ftirerek geli\u015ftirilmi\u015ftir; Scopus, PubMed veya WoS\u2019dan daha geni\u015f bir yelpazede, daha do\u011fru ve daha kolay veri analizi yapmaya imk\u00e2n vermektedir. Bu \u00f6zellikler, akademik gereksinimler, t\u0131bbi literat\u00fcr ara\u015ft\u0131rmas\u0131 ve al\u0131nt\u0131 analizi i\u00e7in daha yararl\u0131d\u0131r (11,12). Scopus veritaban\u0131nda sonu\u00e7lar; belge t\u00fcr\u00fc, kaynak ba\u015fl\u0131\u011f\u0131, yazar ad\u0131, yay\u0131n y\u0131l\u0131 ve konu alan\u0131na g\u00f6re taranabilir. Ayr\u0131ca sonu\u00e7lar aras\u0131nda yeni bir arama ba\u015flat\u0131labilmesinin yan\u0131 s\u0131ra t\u00fcm veriler d\u0131\u015fa aktar\u0131labilmektedir (12,13). Ayn\u0131 tarihte, ayn\u0131 anahtar kelimeler ve ayn\u0131 filtreler uygulanarak yapt\u0131\u011f\u0131m\u0131z taramalarda; Pubmed 14, WoS 14 ve Scopus 40 yay\u0131n sonucu verdi.\u00a0 <\/span>\u00c7al\u0131\u015fmam\u0131zda, di\u011fer veritabanlar\u0131na g\u00f6re daha \u00e7ok avantaja sahip olmas\u0131 ve daha \u00e7ok yay\u0131n sonucu vermesi nedeniyle Scopus tercih edildi.<\/p>\n

\u00c7al\u0131\u015fma kapsam\u0131nda, HIV\/AIDS ile ili\u015fkili HHV-8 infeksiyonuna \u00f6zg\u00fc anahtar kelimeler kullan\u0131larak T\u00fcrkiye\u2019den yap\u0131lan bilimsel yay\u0131nlar 2001-2020 d\u00f6nemi i\u00e7in analiz edildi. Analiz d\u00f6neminin ilk y\u0131l\u0131 olan 2001 \u00fclkemizde HIV\/AIDS ile ili\u015fkili HHV-8 infeksiyonu kapsam\u0131nda yay\u0131n yap\u0131lan ilk y\u0131ld\u0131r. \u00c7al\u0131\u015fmam\u0131z 2021 y\u0131l\u0131nda yap\u0131ld\u0131\u011f\u0131 i\u00e7in de bir y\u0131l\u0131n t\u00fcm verilerini alabildi\u011fimiz 2020 y\u0131l\u0131 son y\u0131l olarak al\u0131nd\u0131. Scopus\u2019ta yap\u0131lan son arama sorgusu g\u00f6r\u00fcnt\u00fcs\u00fc a\u015fa\u011f\u0131daki gibidir:<\/p>\n

\u2018TITLE-ABS-KEY (\u201cacquired immunodeficiency syndrome\u201d OR \u201chuman immunodeficiency virus\u201d OR \u201caids\u201d\u00a0 <\/span>OR\u00a0 <\/span>\u201chiv\u201d )\u00a0 <\/span>AND\u00a0 <\/span>( \u201cKSHV\u201d\u00a0 <\/span>OR\u00a0 <\/span>\u201cHHV-8\u201d\u00a0 <\/span>OR\u00a0 <\/span>\u201ckaposi\u2019s sarcoma associated herpes virus\u201d\u00a0 <\/span>OR\u00a0 <\/span>\u201chuman herpesvirus 8\u201d )\u00a0 <\/span>AND\u00a0 <\/span>( PUBYEAR\u00a0 <\/span><\u00a0 <\/span>2021 )\u00a0 <\/span>AND\u00a0 <\/span>( LIMIT-TO ( AFFILCOUNTRY ,\u00a0 <\/span>\u201cTurkey\u201d ) )\u2019\u00a0<\/span><\/p>\n

Literat\u00fcr taramas\u0131 4 Ekim 2021\u2019de ger\u00e7ekle\u015ftirildi ve yay\u0131n say\u0131s\u0131n\u0131n s\u00fcrekli g\u00fcncellenmesi nedeniyle t\u00fcm veriler ayn\u0131 g\u00fcn i\u00e7inde al\u0131nd\u0131. Veriler Microsoft Excel tablosuna kaydedildi ve istatistiksel analizler Microsoft Excel 365 program\u0131 (Microsoft Corp. Washington, ABD) ile yap\u0131ld\u0131. Toplanan verilerin analizinde frekans, y\u00fczde ve aritmetik ortalama de\u011ferleri hesapland\u0131.\u00a0<\/span><\/p>\n

Elde edilen verilerin nicel ve nitel analizi uygun bibliyometrik g\u00f6stergeler kullan\u0131larak y\u0131llara g\u00f6re; yay\u0131n say\u0131s\u0131, alan, yay\u0131n dili, dergi ad\u0131, \u00fclke, yazarlar, yay\u0131m y\u0131l\u0131, yay\u0131mland\u0131\u011f\u0131 kurum, at\u0131f say\u0131s\u0131 bak\u0131m\u0131ndan de\u011ferlendirildi. Ayr\u0131ca, veri setindeki t\u00fcm anahtar kelimeleri toplayan ve ortak bir kelime a\u011f\u0131 olu\u015fturarak g\u00f6rselle\u015ftiren VOSviewer version 1.6.16 program\u0131 (Leiden University\u2019s Centre for Science and Technology Studies, Leiden, Hollanda) kullan\u0131larak, anahtar kelimelerin analizi ile ara\u015ft\u0131rma ilgi alanlar\u0131 ve ili\u015fkileri belirlendi (14).\u00a0<\/span><\/p>\n

Yap\u0131lan \u00e7al\u0131\u015fma Helsinki Deklarasyonu\u2019na uygun olarak ger\u00e7ekle\u015ftirildi. \u00c7al\u0131\u015fma y\u00f6ntemi dok\u00fcman inceleme tekni\u011fi oldu\u011fu i\u00e7in etik kurul onay\u0131 al\u0131nmad\u0131. \u00a0<\/span><\/p>\n

BULGULAR<\/h2>\n
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Tablo 1.<\/strong> En \u00c7ok At\u0131f Alan \u0130lk 10 Yay\u0131n<\/p><\/div>\n

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Tablo 2.<\/strong> Vosviewer Program\u0131 Analiz Sonu\u00e7lar\u0131<\/p><\/div>\n

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\u015eekil 1.<\/strong> 2001-2020 Y\u0131llar\u0131 Aras\u0131nda Yay\u0131n ve At\u0131f Say\u0131lar\u0131<\/p><\/div>\n

\"\"<\/a>

\u015eekil 2.<\/strong> Kullan\u0131m S\u0131kl\u0131\u011f\u0131 \u0130kiden Fazla Olan 14 Anahtar Kelimenin A\u011f Haritas\u0131<\/p><\/div>\n

\"\"<\/a>

\u015eekil 3.<\/strong> 1994-2020 Y\u0131llar\u0131 Aras\u0131nda D\u00fcnya Genelinde Yap\u0131lan Yay\u0131n Say\u0131lar\u0131<\/p><\/div>\n

\"\"<\/a>

\u015eekil 4.<\/strong> Bilimsel Yay\u0131nlar\u0131n \u00dclkelere G\u00f6re Da\u011f\u0131l\u0131m\u0131<\/p><\/div>\n

\"\"<\/a>

\u015eekil 5.<\/strong> \u0130lk Be\u015fte Olan \u00dclkelerin ve T\u00fcrkiye\u2019nin 2001-2020 Y\u0131llar\u0131 Aras\u0131nda Literat\u00fcre Sundu\u011fu Katk\u0131<\/p><\/div>\n

Yap\u0131lan \u00e7al\u0131\u015fmada, sunulan arama stratejisi ile Scopus veritaban\u0131nda 2001-2020 y\u0131llar\u0131 aras\u0131nda T\u00fcrkiye kaynakl\u0131 toplam 40 bilimsel yay\u0131n tespit edildi. T\u00fcrkiye\u2019de, HIV\/AIDS ile ili\u015fkili HHV-8\/KSHV infeksiyonuna ait ilk yay\u0131nlar\u0131n (n=2, %5) 2001 y\u0131l\u0131nda; en fazla say\u0131da yay\u0131n\u0131n (n=5, %12.5) ise 2013 ve 2020 y\u0131llar\u0131 aras\u0131nda yay\u0131mland\u0131\u011f\u0131 g\u00f6r\u00fcld\u00fc (\u015eekil 1). \u0130ngilizce olarak yay\u0131mlanan \u00e7al\u0131\u015fmalar\u0131n say\u0131s\u0131 33 (%82.5) olup 7 (%17.5) \u00e7al\u0131\u015fma T\u00fcrk\u00e7e haz\u0131rlanm\u0131\u015ft\u0131. Yay\u0131nlar\u0131n 3 (%7.5)\u2019\u00fc Mikrobiyoloji B\u00fclteni\u2019<\/i>nde, ikisi Acta Medica Mediterranea<\/i>\u2019de ve geriye kalan 35 yay\u0131n\u0131n her biri farkl\u0131 dergilerde yay\u0131mlanm\u0131\u015ft\u0131. S\u00f6z konusu yay\u0131nlar\u0131n 33 (%82.5)\u2019\u00fc \u00f6zg\u00fcn ara\u015ft\u0131rma makalesi, 4 (%10)\u2019\u00fc edit\u00f6re mektup ve 3 (%7.5)\u2019\u00fc derlemeydi. Bilimsel alanlar\u0131n da\u011f\u0131l\u0131m\u0131na bak\u0131ld\u0131\u011f\u0131nda, 38 (%95) t\u0131p, 5 (%12.5) imm\u00fcnoloji ve mikrobiyoloji ve 4 (%10) biyokimya, genetik ve molek\u00fcler biyoloji yay\u0131n\u0131 tespit edildi. Bilimsel literat\u00fcre en \u00e7ok katk\u0131 sunan kurum 13 (%32.5) yay\u0131n ile \u0130stanbul \u00dcniversitesi olup onu 4 (%10) yay\u0131nla Hacettepe \u00dcniversitesi ve 3 (%7.5) yay\u0131nla Ankara \u00dcniversitesi takip ediyordu. Bak\u0131rk\u00f6y Dr. Sadi Konuk E\u011fitim ve Ara\u015ft\u0131rma Hastanesi\u2019nden Ay\u015fe Kavak, Ac\u0131badem Mehmet Ali Ayd\u0131nlar \u00dcniversitesi\u2019nden Tan\u0131l Kocag\u00f6z ve T\u00fclay Tecimer iki\u015fer yay\u0131n ile literat\u00fcre en \u00e7ok katk\u0131 yapan yazarlard\u0131. Tespit edilen yay\u0131nlar toplam 203 at\u0131f alm\u0131\u015ft\u0131r. T\u00fcm yay\u0131nlara bak\u0131ld\u0131\u011f\u0131nda en \u00e7ok at\u0131f (n=39; %19.2) 2019 y\u0131l\u0131nda yap\u0131lm\u0131\u015f olup en fazla at\u0131f alan (n=42; %20.7) be\u015f yay\u0131n 2013 y\u0131l\u0131nda yay\u0131mlanm\u0131\u015ft\u0131r (\u015eekil 1). <\/span>Journal of Pathology Microbiology and Immunology<\/i>\u2019de yay\u0131mlanan \u201cHuman herpes virus 8-unrelated primary effusion lymphoma-like lymphoma: Report of a rare case and review of the literature\u201d ba\u015fl\u0131kl\u0131 makale en fazla at\u0131f (n=42) alan \u00e7al\u0131\u015fmad\u0131r (15). En fazla at\u0131f alan ilk on yay\u0131n ve at\u0131f say\u0131lar\u0131 Tablo 1\u2019de verildi.<\/p>\n

Vosviewer program\u0131n\u0131 kullanarak yapt\u0131\u011f\u0131m\u0131z anahtar kelime analiziyle; anahtar kelimelerin kullan\u0131m s\u0131kl\u0131\u011f\u0131, birbirleri ile ili\u015fkisi ve olu\u015fan k\u00fcmelerin konular\u0131 belirlendi. \u015eekil 2\u2019de kullan\u0131m s\u0131kl\u0131\u011f\u0131 ikiden fazla olan 14 anahtar kelimenin a\u011f haritas\u0131 verildi. B\u00fcy\u00fck boyutlu daireler y\u00fcksek s\u0131kl\u0131kta g\u00f6r\u00fcnen anahtar kelimeleri, daireler aras\u0131ndaki \u00e7izgiler anahtar kelimeler aras\u0131ndaki ba\u011flant\u0131n\u0131n varl\u0131\u011f\u0131n\u0131 g\u00f6stermektedir. \u0130ki terim aras\u0131ndaki mesafe, ili\u015fkinin yak\u0131nl\u0131\u011f\u0131n\u0131 g\u00f6stermektedir (\u00e7izgi ne kadar k\u0131sa ise ili\u015fki o kadar yak\u0131nd\u0131r). Anahtar kelimelerin k\u00fcme analizi a\u00e7\u0131s\u0131ndan, her renk bir k\u00fcmeyi temsil etmektedir. Analiz sonucu olu\u015fan be\u015f k\u00fcme, k\u00fcmeler i\u00e7indeki anahtar kelimeler, anahtar kelimelerin ba\u011flant\u0131 ve kullan\u0131m s\u0131kl\u0131klar\u0131 ve k\u00fcmelerin ili\u015fkili oldu\u011fu konular Tablo 2\u2019de verildi.<\/p>\n

Arama stratejimize uygun olarak ayn\u0131 g\u00fcn ve \u00fclke s\u0131n\u0131rlamas\u0131 olmaks\u0131z\u0131n yapt\u0131\u011f\u0131m\u0131z tarama sonucunda; d\u00fcnya genelinde 1994-2020 y\u0131llar\u0131 aras\u0131nda toplam 6319 bilimsel yay\u0131n yap\u0131ld\u0131\u011f\u0131 tespit edildi; en fazla yay\u0131n 296 (%4.68) yay\u0131n ile 2011 ve 2012 y\u0131llar\u0131 aras\u0131nda yap\u0131lm\u0131\u015ft\u0131 (\u015eekil 3).\u00a0 <\/span>S\u00f6z konusu d\u00f6nemde, literat\u00fcre 120\u2019den fazla \u00fclkeden makale sunulmu\u015f olup Amerika Birle\u015fik Devletleri (ABD) 2876 (%45.51) yay\u0131nla ilk s\u0131rada yer al\u0131rken, onu s\u0131ras\u0131yla \u0130talya ve Birle\u015fik Krall\u0131k izlemi\u015fti. \u00dclke ba\u011flant\u0131s\u0131 tan\u0131mlanmam\u0131\u015f toplam 141 makale belirlendi. Bilimsel yay\u0131nlarda \u00f6nde olan 10 \u00fclkenin ve T\u00fcrkiye\u2019nin yay\u0131n say\u0131lar\u0131 \u015eekil 4\u2019te verildi; T\u00fcrkiye %0.63\u2019l\u00fck bir oranla 29. s\u0131rada yer alm\u0131\u015ft\u0131r. Yay\u0131n say\u0131lar\u0131na g\u00f6re, ilk be\u015fte olan \u00fclkelerin ve T\u00fcrkiye\u2019nin 2001-2020 y\u0131llar\u0131 aras\u0131nda literat\u00fcre sundu\u011fu katk\u0131 \u015eekil 5\u2019te verildi.\u00a0<\/span><\/p>\n

\u0130RDELEME<\/h2>\n

Kaposi sarkomu, AIDS\u2019li hastalarda \u00f6nde gelen bir neoplazi olup geli\u015fimi i\u00e7in HIV infeksiyonunun \u00f6nemli bir risk fakt\u00f6r\u00fc oldu\u011fu bilinmektedir. \u00d6zellikle HIV\/AIDS\u2019li hastalarda HHV-8\/KSHV infeksiyonunun KS etkeni oldu\u011fu bilinmektedir (16). HHV-8\/KSHV infeksiyonu ile ilgili ara\u015ft\u0131rmalar virusun tan\u0131mlanmas\u0131ndan sonra artm\u0131\u015ft\u0131r ancak s\u00f6z konusu ara\u015ft\u0131rmalar\u0131n bilimsel \u00fcretim boyutu hakk\u0131nda sistematik veri toplamaya y\u00f6nelik \u00e7ok az \u00e7al\u0131\u015fma bildirilmi\u015ftir (10). Bu ba\u011flamda, HHV-8\/KSHV infeksiyonu ile ilgili ara\u015ft\u0131rmalar\u0131 incelemek ve bu \u00e7al\u0131\u015fmalar\u0131n \u00f6zelliklerini tan\u0131mlamak i\u00e7in temel bibliyometrik verilere gereksinim vard\u0131r. \u00c7al\u0131\u015fmam\u0131zda, T\u00fcrkiye\u2019den literat\u00fcre sunulan HIV\/AIDS ile ili\u015fkili HHV-8 infeksiyonu yay\u0131nlar\u0131n\u0131n bibliyometrik bir de\u011ferlendirmesi yap\u0131ld\u0131. Yapt\u0131\u011f\u0131m\u0131z literat\u00fcr tarama sonu\u00e7lar\u0131na g\u00f6re bu \u00e7al\u0131\u015fma HIV\/AIDS ile ili\u015fkili HHV-8 infeksiyonu kapsam\u0131nda ilk bibliyometrik analizdir.<\/p>\n

D\u00fcnya genelinde, HIV ile ya\u015fayan bireylerdeki HHV-8\/KSHV seroprevalans\u0131 kapsam\u0131nda yap\u0131lm\u0131\u015f pek \u00e7ok \u00e7al\u0131\u015fma mevcuttur. Rohner ve arkada\u015flar\u0131n\u0131n (17) yapt\u0131\u011f\u0131 meta-analiz \u00e7al\u0131\u015fmas\u0131nda, Sahra alt\u0131 Afrika, Kuzey ve G\u00fcney Amerika, Avrupa, Asya ve Avustralya b\u00f6lgelerinden HIV pozitif ve HIV negatif bireyler aras\u0131nda HHV-8 seroprevalans\u0131n\u0131n ara\u015ft\u0131r\u0131ld\u0131\u011f\u0131 yay\u0131nlar analiz edilmi\u015f ve HIV pozitif bireylerin HHV-8 seropozitifli\u011finin %47 oran\u0131yla anlaml\u0131 d\u00fczeyde y\u00fcksek bulundu\u011fu bildirilmi\u015ftir; HIV negatif bireyler aras\u0131nda bu oran %24\u2019t\u00fcr.\u00a0 <\/span>\u00dclkemizde yap\u0131lan \u00e7al\u0131\u015fmalarda ise HIV pozitif bireyler aras\u0131nda HHV-8 seropozitifli\u011fi oran\u0131 %21-%28 aras\u0131nda bildirilmi\u015ftir; s\u00f6z konusu k\u0131s\u0131tl\u0131 say\u0131da prevalans \u00e7al\u0131\u015fmas\u0131nda HIV pozitif bireylerde HHV-8 prevalans\u0131n\u0131n d\u00fc\u015f\u00fck olmad\u0131\u011f\u0131 g\u00f6r\u00fclm\u00fc\u015ft\u00fcr (8,18,19). \u00dclkemizde konuyla ilgili daha fazla ara\u015ft\u0131rmaya ihtiya\u00e7 oldu\u011fu yapt\u0131\u011f\u0131m\u0131z literat\u00fcr taramas\u0131nda a\u00e7\u0131k\u00e7a g\u00f6r\u00fcld\u00fc. Bibliyometrik analiz literat\u00fcrdeki eksiklikleri g\u00f6rmek ad\u0131na \u00f6nemli bir y\u00f6ntemdir. Ulusal d\u00fczeyde HIV\/AIDS ile ili\u015fkili HHV-8 infeksiyonu \u00e7al\u0131\u015fmalar\u0131n\u0131n art\u0131r\u0131lmas\u0131 gerekti\u011fi de bu bibliyometrik analiz sonucunda anla\u015f\u0131ld\u0131.<\/p>\n

\u00c7al\u0131\u015fmam\u0131zda, HIV\/AIDS ile ili\u015fkili HHV-8 infeksiyonu kapsam\u0131nda \u00fclkemizde yap\u0131lan ilk yay\u0131n\u0131n 2001 y\u0131l\u0131nda sunuldu\u011funu ve toplamda 40 yay\u0131n\u0131n oldu\u011funu tespit ettik. D\u00fcnyadaki durumu de\u011ferlendirdi\u011fimizde ise konuya ili\u015fkin ilk yay\u0131n\u0131n 1994 y\u0131l\u0131nda sunuldu\u011funu ve toplamda 6319 yay\u0131n\u0131n bulundu\u011funu g\u00f6rd\u00fck. T\u00fcrkiye\u2019den sunulan 40 yay\u0131n \u00fclkemizi d\u00fcnya s\u0131ralamas\u0131nda 29. s\u0131raya yerle\u015ftirmi\u015ftir. Yay\u0131n say\u0131s\u0131 ortalamalar\u0131n\u0131n ilk 10\u2019da yer alan \u00fclkeler i\u00e7in 594 ve ilk be\u015fte yer alan \u00fclkeler i\u00e7in ise 980 oldu\u011fu g\u00f6z \u00f6n\u00fcnde bulunduruldu\u011funda, \u00fclkemizin d\u00fcnya literat\u00fcr\u00fcne yapt\u0131\u011f\u0131 katk\u0131n\u0131n \u00e7ok az oldu\u011fu a\u00e7\u0131kt\u0131r. En fazla yay\u0131n\u0131n yap\u0131ld\u0131\u011f\u0131 2013 ve 2020 y\u0131llar\u0131 aras\u0131nda, yay\u0131n say\u0131lar\u0131n\u0131n bir \u00f6nceki y\u0131la g\u00f6re art\u0131\u015f\u0131 s\u0131ras\u0131yla %400 ve %150 oranlar\u0131nda ger\u00e7ekle\u015fmi\u015ftir. Genel yay\u0131n say\u0131s\u0131 art\u0131\u015f oranlar\u0131na bakt\u0131\u011f\u0131m\u0131zda en fazla art\u0131\u015f\u0131n 2013 y\u0131l\u0131nda oldu\u011funu g\u00f6rmekteyiz. 2013 y\u0131l\u0131ndaki bu art\u0131\u015f\u0131n sebebi d\u00fcnya literat\u00fcr\u00fcnde en y\u00fcksek say\u0131da yay\u0131n\u0131n yap\u0131lm\u0131\u015f oldu\u011fu 2011 ve 2012 y\u0131llar\u0131na ba\u011flanabilir. Bu d\u00f6nemde d\u00fcnya genelinde konuyla ilgili yap\u0131lan ara\u015ft\u0131rmalar\u0131n artmas\u0131, \u00fclkemizdeki ara\u015ft\u0131rmac\u0131lar\u0131n da konuya y\u00f6nelik ilgilerini art\u0131rm\u0131\u015f olabilir. Hem \u00fclkemizde hem de d\u00fcnyada yay\u0131n say\u0131s\u0131nda 2019 y\u0131l\u0131nda bir azalma, 2020 y\u0131l\u0131nda ise bir art\u0131\u015f oldu\u011fu g\u00f6r\u00fclmektedir. T\u00fcm bu g\u00f6zlemlere dayanarak, \u00fclkemizdeki ara\u015ft\u0131rmac\u0131lar\u0131n konuya ili\u015fkin yay\u0131n yapma motivasyonlar\u0131n\u0131n d\u00fcnya literat\u00fcr\u00fcnden etkilendi\u011fini s\u00f6yleyebiliriz.\u00a0<\/span><\/p>\n

Analizimiz sonucu, HIV\/AIDS ile ili\u015fkili HHV-8 infeksiyonu konulu yay\u0131nlar\u0131n \u00e7ok b\u00fcy\u00fck bir b\u00f6l\u00fcm\u00fcn\u00fcn \u0130ngilizce yaz\u0131ld\u0131\u011f\u0131 g\u00f6r\u00fcld\u00fc. D\u00fcnya genelinde de ara\u015ft\u0131rma dili olarak kabul g\u00f6ren \u0130ngilizce \u00fclkemizdeki ara\u015ft\u0131rmac\u0131lar\u0131n yay\u0131nlar\u0131 i\u00e7in de ge\u00e7erlidir. \u00c7al\u0131\u015fmam\u0131zda, en fazla say\u0131da olan yay\u0131n t\u00fcr\u00fcn\u00fcn \u00f6zg\u00fcn ara\u015ft\u0131rma makalesi oldu\u011fu ve b\u00fcy\u00fck \u00f6l\u00e7\u00fcde t\u0131p alan\u0131nda yay\u0131n yap\u0131ld\u0131\u011f\u0131 tespit edildi. Wang ve arkada\u015flar\u0131 (10) taraf\u0131ndan HHV-8\/KSHV infeksiyonu ile ilgili olarak yap\u0131lm\u0131\u015f bibliyometrik analizde, yay\u0131nlar\u0131n b\u00fcy\u00fck \u00e7o\u011funlu\u011funun \u00f6zg\u00fcn ara\u015ft\u0131rma makalesi olmas\u0131 ve \u0130ngilizce yaz\u0131lmas\u0131 bizim ara\u015ft\u0131rmam\u0131z\u0131n bulgular\u0131 ile benzerdir. Yay\u0131nlar\u0131n \u00e7o\u011funlukla t\u0131p alan\u0131nda yap\u0131lm\u0131\u015f olmas\u0131 HHV-8 ve HIV infeksiyonlar\u0131n\u0131n insan sa\u011fl\u0131\u011f\u0131yla ili\u015fkili olmas\u0131 nedeniyle beklenilen bir durumdur.\u00a0<\/span><\/p>\n

Ara\u015ft\u0131rmac\u0131lar konuyla ilgili \u00e7al\u0131\u015fmalar\u0131n\u0131 yay\u0131mlatmak i\u00e7in en \u00e7ok Mikrobiyoloji B\u00fclteni<\/i>\u2019ni tercih etmi\u015ftir. Mikrobiyoloji B\u00fclteni<\/i>, Ankara Mikrobiyoloji Derne\u011fi\u2019nin bilimsel yay\u0131n organ\u0131d\u0131r ve hedef kitlesi, t\u0131bbi\/klinik mikrobiyoloji, infeksiyon hastal\u0131klar\u0131 ve halk sa\u011fl\u0131\u011f\u0131 alanlar\u0131ndan ara\u015ft\u0131rmac\u0131lard\u0131r. Yay\u0131n dili T\u00fcrk\u00e7e olan dergi kapsaml\u0131 \u0130ngilizce \u00f6zet k\u0131sm\u0131 i\u00e7ermektedir. Hekimo\u011flu ve arkada\u015flar\u0131n\u0131n (20) HIV ve AIDS ile ilgili olarak yapt\u0131\u011f\u0131 bibliyometrik analizde en \u00e7ok yay\u0131n yap\u0131lan dergiler aras\u0131nda Mikrobiyoloji B\u00fclteni<\/i> ikinci s\u0131rada bildirilmi\u015ftir. T\u00fcm bu veriler \u0131\u015f\u0131\u011f\u0131nda, ara\u015ft\u0131rmac\u0131lar\u0131n genellikle b\u00f6lgesel \/ ulusal ara\u015ft\u0131rmalar yapt\u0131klar\u0131 ve derginin hem ulusal hem de uluslararas\u0131 bir\u00e7ok veritaban\u0131nda tarat\u0131lmas\u0131 sebebi ile bu dergiyi tercih ettikleri d\u00fc\u015f\u00fcn\u00fclmektedir. En fazla yay\u0131n\u0131n\u0131n \u0130stanbul \u00dcniversitesi\u2019ndeki ara\u015ft\u0131rmac\u0131lar taraf\u0131ndan sunulmu\u015f olmas\u0131 ve en \u00e7ok yay\u0131n yapan yazarlar\u0131n \u0130stanbul\u2019daki kurumlarda \u00e7al\u0131\u015fmas\u0131, \u00fclkemizde \u0130stanbul\u2019daki ara\u015ft\u0131rmac\u0131lar\u0131n HIV\/AIDS ile ili\u015fkili HHV-8 infeksiyonu konulu ara\u015ft\u0131rmalara daha fazla ilgi duydu\u011funu g\u00f6stermi\u015ftir. Hekimo\u011flu ve arkada\u015flar\u0131n\u0131n (20) yapt\u0131\u011f\u0131 \u00e7al\u0131\u015fmada, yay\u0131nlarda ilk isim olan yazarlar\u0131n da en \u00e7ok \u0130stanbul\u2019da bulunan kurumlarda \u00e7al\u0131\u015ft\u0131\u011f\u0131 bildirilmi\u015ftir. Kaposi sarkomu infeksiyonlar\u0131n\u0131n daha \u00e7ok HIV\/AIDS ile ili\u015fkili olmas\u0131, \u0130stanbul\u2019daki ara\u015ft\u0131rmac\u0131lar\u0131 HIV\/AIDS ile ili\u015fkili HHV-8 infeksiyonu konular\u0131nda da ara\u015ft\u0131rma yapmaya y\u00f6nlendirmi\u015f olabilir.<\/p>\n

Yay\u0131nlara yap\u0131lan at\u0131flara bakt\u0131\u011f\u0131m\u0131zda, HIV\/AIDS ile ili\u015fkili HHV-8 infeksiyonu konulu yay\u0131nlarda toplam 203 at\u0131f tespit edilmi\u015f olup yay\u0131n ba\u015f\u0131na d\u00fc\u015fen ortalama at\u0131f say\u0131s\u0131 yakla\u015f\u0131k be\u015fti. En fazla at\u0131f, en \u00e7ok makalenin yay\u0131nland\u0131\u011f\u0131 2013 y\u0131l\u0131ndaki yay\u0131nlara yap\u0131lm\u0131\u015ft\u0131. Bu durum, yay\u0131n say\u0131s\u0131n\u0131n di\u011fer y\u0131llara g\u00f6re daha fazla olmas\u0131 nedeniyle beklenilen bir sonu\u00e7tur. En fazla at\u0131f alan makale 2009 y\u0131l\u0131nda yay\u0131mlanm\u0131\u015ft\u0131r ve o y\u0131l yay\u0131mlananlar aras\u0131nda at\u0131f alan tek makaledir. Genel olarak ulusal verilerle yap\u0131lan \u00e7al\u0131\u015fmalar\u0131n en \u00e7ok at\u0131f alan yay\u0131nlar oldu\u011fu g\u00f6r\u00fclm\u00fc\u015ft\u00fcr. Bu yay\u0131nlar\u0131n t\u00fcm\u00fcn\u00fcn \u0130ngilizce yaz\u0131ld\u0131\u011f\u0131 ve uluslararas\u0131 dergilerde yay\u0131mland\u0131klar\u0131 g\u00f6z \u00f6n\u00fcne al\u0131nd\u0131\u011f\u0131nda, yay\u0131n dilinin ve se\u00e7ilen derginin, yay\u0131nlar\u0131n g\u00f6r\u00fcn\u00fcrl\u00fc\u011f\u00fcn\u00fc etkileyen fakt\u00f6rler oldu\u011funu d\u00fc\u015f\u00fcnebiliriz.\u00a0<\/span><\/p>\n

VOSviewer program\u0131 ile yapt\u0131\u011f\u0131m\u0131z anahtar kelime a\u011f analizi sonucu en s\u0131k kullan\u0131lan anahtar kelimenin \u201ckaposi\u2019s sarcoma\u201d oldu\u011fu g\u00f6r\u00fcld\u00fc. Bu anahtar kelimenin; \u201chuman herpesvirus-8\u201d, \u201chhv-8\u201d, \u201ctreatment\u201d anahtar kelimeleri ile ba\u011flant\u0131l\u0131 ve \u201cradiotherapy\u201d anahtar kelimesiyle hem ba\u011flant\u0131l\u0131 hem de yak\u0131n ili\u015fkili oldu\u011fu tespit edildi. Farkl\u0131 anahtar kelimeler ile en \u00e7ok ba\u011flant\u0131s\u0131 (6 ba\u011flant\u0131) olan anahtar kelime be\u015f kez kullan\u0131lm\u0131\u015f olan \u201chhv-8\u201d idi. En yak\u0131n ili\u015fki i\u00e7inde bulunan anahtar kelimelerin \u201cebv\u201d ve \u201cprimary effusion lymphoma\u201d oldu\u011fu g\u00f6r\u00fcld\u00fc. Analiz sonucu en \u00e7ok \u00e7al\u0131\u015fma be\u015finci k\u00fcmede (mor) idi ve mor k\u00fcmenin temas\u0131n\u0131n KS\u2019da radyoterapi tedavisiyle ilgili ara\u015ft\u0131rmalar oldu\u011fu anla\u015f\u0131ld\u0131. HIV ile ili\u015fkili HHV-8 infeksiyonu \u00e7al\u0131\u015fmalar\u0131n\u0131n yer ald\u0131\u011f\u0131 \u00fc\u00e7\u00fcnc\u00fc (mavi) k\u00fcmede yer alan \u201chhv-8\u201d anahtar kelimesi en fazla ba\u011flant\u0131s\u0131 olan anahtar kelimedir. Bu sonu\u00e7 yapt\u0131\u011f\u0131m\u0131z bibliyometrik analizin amac\u0131yla uyumludur. Ancak ana hedefimizle do\u011frudan ilgili olan mavi k\u00fcmenin b\u00fcy\u00fck olmay\u0131\u015f\u0131 bize \u00fclkemizde konu ile ilgili yeterli \u00e7al\u0131\u015fman\u0131n yap\u0131lmad\u0131\u011f\u0131n\u0131 g\u00f6sterdi. Anahtar kelime a\u011f analizi sonu\u00e7lar\u0131, \u00f6zellikle prevalans ve tedaviye y\u00f6nelik ara\u015ft\u0131rmalar\u0131n da az oldu\u011funu g\u00f6stermektedir. Daha \u00f6nce belirtildi\u011fi gibi \u00fclkemizde yap\u0131lan az say\u0131da \u00e7al\u0131\u015fmada, HIV ile ya\u015fayan bireylerde HHV-8 seroprevalans\u0131n\u0131n d\u00fc\u015f\u00fck olmad\u0131\u011f\u0131 bildirilmi\u015ftir (8,18,19). \u00d6zellikle HIV ile ya\u015fayan bireylerdeki HHV-8 prevalans\u0131n\u0131n daha net ortaya konulmas\u0131 ad\u0131na ulusal d\u00fczeyde HIV ile ili\u015fkili HHV-8 infeksiyonu kapsam\u0131nda epidemiyolojik \u00e7al\u0131\u015fmalara ihtiya\u00e7 oldu\u011fu a\u00e7\u0131kt\u0131r. \u00dclkemizde yap\u0131lacak epidemiyolojik \u00e7al\u0131\u015fmalar\u0131n verileriyle ara\u015ft\u0131rmac\u0131lar\u0131n tedaviye y\u00f6nelik \u00e7al\u0131\u015fmalar\u0131n\u0131n da artmas\u0131 sa\u011flanacakt\u0131r.<\/p>\n

Sundu\u011fumuz bibliyometrik analiz; kapsaml\u0131 bir veri taban\u0131 ara\u015ft\u0131rmas\u0131 olarak g\u00fcncel literat\u00fcr verilerinin tan\u0131mlanmas\u0131 ve akademisyenlerin \u00e7al\u0131\u015fmalar\u0131nda odaklanmalar\u0131 gereken noktalar\u0131n belirlemesi a\u00e7\u0131s\u0131ndan yararl\u0131 bir \u00e7al\u0131\u015fmad\u0131r. Ancak \u00e7al\u0131\u015fmam\u0131z\u0131n s\u0131n\u0131rl\u0131l\u0131klar\u0131 vard\u0131r. Scopus\u2019ta dizinlenmeyen ve \u00f6zellikle T\u00fcrkiye\u2019de yay\u0131mlanan dergiler \u00e7al\u0131\u015fmam\u0131z kapsam\u0131 d\u0131\u015f\u0131nda kald\u0131. Tek bir veritaban\u0131 \u00fczerinden tarama yapmak konu ile ilgili baz\u0131 yay\u0131nlar\u0131n de\u011ferlendirme d\u0131\u015f\u0131nda kalmas\u0131na da yol a\u00e7maktad\u0131r. Ba\u015fl\u0131k, \u00f6zet ve anahtar kelimelerle tarama yap\u0131lmas\u0131 do\u011fru verileri sa\u011flamakla birlikte konuyla ilgili b\u00fct\u00fcn yay\u0131nlara ula\u015fmay\u0131 engelleyebilmektedir. At\u0131f de\u011ferlendirmesi de sadece Scopus veritaban\u0131yla s\u0131n\u0131rl\u0131d\u0131r.<\/p>\n

Sonu\u00e7 olarak; son y\u0131llarda bir art\u0131\u015f olmakla birlikte bibliyometrik analiz y\u00f6ntemi di\u011fer y\u00f6ntemlere k\u0131yasla daha az kullan\u0131lmaktad\u0131r. \u00c7al\u0131\u015fmam\u0131z\u0131n, k\u0131s\u0131tl\u0131l\u0131klar\u0131na ra\u011fmen ihtiya\u00e7 duyulan bir alanda yap\u0131lm\u0131\u015f olmas\u0131, alan\u0131m\u0131zdaki bilimsel \u00fcretkenlikle ilgili eksik ve g\u00fc\u00e7l\u00fc y\u00f6nleri ortaya koymas\u0131, sorunlar\u0131n belirlenmesi ve \u00e7\u00f6z\u00fcm \u00f6nerilerini sunmas\u0131, ileride planlanacak proje ve \u00e7al\u0131\u015fmalara yol g\u00f6stermesi a\u00e7\u0131s\u0131ndan \u00f6nemli oldu\u011funu d\u00fc\u015f\u00fcn\u00fcyoruz. Bu t\u00fcr analizlerin periyodik olarak tekrarlanmas\u0131, uluslararas\u0131 kar\u015f\u0131la\u015ft\u0131rmalarla birlikte sunulmas\u0131, alan\u0131m\u0131zdaki bilimsel \u00e7al\u0131\u015fmalar\u0131n nicelik ve nitelik a\u00e7\u0131s\u0131ndan geli\u015fimine katk\u0131 sa\u011flayacakt\u0131r.<\/p>\n","protected":false},"excerpt":{"rendered":"

G\u0130R\u0130\u015e \u0130nsan herpes virusu 8 (human herpes virus 8-HHV-8) veya di\u011fer ad\u0131yla Kaposi sarkomu herpes virusu (KSHV), Rhadinovirus cinsine ait gamma herpes virus ailesindendir. Kan ve kan \u00fcr\u00fcnleri, organ nakli, t\u00fck\u00fcr\u00fck ve cinsel temasla bula\u015fabilmekte ve lenfoid dokularda latent olarak kalmaktad\u0131r (1). \u0130mm\u00fcns\u00fcpresif hastalar\u0131n t\u00fck\u00fcr\u00fck ve oral mukozas\u0131nda bulunabilen HHV-8 virusu onkojenik bir virus olup […]<\/p>\n","protected":false},"author":4,"featured_media":26860,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"footnotes":""},"categories":[5129],"tags":[5684,5685,5163,5686],"class_list":["post-26654","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-ozgun-arastirma","tag-bibliyometrik-analiz","tag-hhv-8","tag-hiv-2","tag-kaposi-sarkomu"],"acf":[],"_links":{"self":[{"href":"https:\/\/www.klimikdergisi.org\/tr\/wp-json\/wp\/v2\/posts\/26654","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.klimikdergisi.org\/tr\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.klimikdergisi.org\/tr\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.klimikdergisi.org\/tr\/wp-json\/wp\/v2\/users\/4"}],"replies":[{"embeddable":true,"href":"https:\/\/www.klimikdergisi.org\/tr\/wp-json\/wp\/v2\/comments?post=26654"}],"version-history":[{"count":4,"href":"https:\/\/www.klimikdergisi.org\/tr\/wp-json\/wp\/v2\/posts\/26654\/revisions"}],"predecessor-version":[{"id":26825,"href":"https:\/\/www.klimikdergisi.org\/tr\/wp-json\/wp\/v2\/posts\/26654\/revisions\/26825"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.klimikdergisi.org\/tr\/wp-json\/wp\/v2\/media\/26860"}],"wp:attachment":[{"href":"https:\/\/www.klimikdergisi.org\/tr\/wp-json\/wp\/v2\/media?parent=26654"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.klimikdergisi.org\/tr\/wp-json\/wp\/v2\/categories?post=26654"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.klimikdergisi.org\/tr\/wp-json\/wp\/v2\/tags?post=26654"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}