{"id":16463,"date":"2021-01-05T01:25:07","date_gmt":"2021-01-04T22:25:07","guid":{"rendered":"https:\/\/www.klimikdergisi.org\/\/2021\/01\/05\/febril-notropenik-hastalarda-bakteriyel-infeksiyonlarin-tanisal-ve-prognostik-bir-gostergesi-olarak-prokalsitoninin-degerlendirilmesi\/"},"modified":"2021-01-05T01:25:07","modified_gmt":"2021-01-04T22:25:07","slug":"febril-notropenik-hastalarda-bakteriyel-infeksiyonlarin-tanisal-ve-prognostik-bir-gostergesi-olarak-prokalsitoninin-degerlendirilmesi","status":"publish","type":"post","link":"https:\/\/www.klimikdergisi.org\/tr\/2021\/01\/05\/febril-notropenik-hastalarda-bakteriyel-infeksiyonlarin-tanisal-ve-prognostik-bir-gostergesi-olarak-prokalsitoninin-degerlendirilmesi\/","title":{"rendered":"Febril N\u00f6tropenik Hastalarda Bakteriyel \u0130nfeksiyonlar\u0131n Tan\u0131sal ve Prognostik Bir G\u00f6stergesi Olarak Prokalsitoninin De\u011ferlendirilmesi"},"content":{"rendered":"<h1>\u00d6zet<\/h1>\n<p> <strong>Ama\u00e7<\/strong>: Maligniteli hastalardaki febril n\u00f6tropeni ataklar\u0131nda prokalsitonin (PCT)\u2019in bakteriyel infeksiyonlar\u0131n tan\u0131sal ve prognostik bir g\u00f6stergesi olarak standard bir parametre olan C-reaktif protein (CRP) ile kar\u015f\u0131la\u015ft\u0131r\u0131l\u0131p de\u011ferlendirilmesi ama\u00e7land\u0131. \u00a0<\/p>\n<p> <strong>Y\u00f6ntemler<\/strong>: Kemoterapiye ba\u011fl\u0131 37 hastadaki 40 febril n\u00f6tropenik atak \u00fc\u00e7 gruba ayr\u0131ld\u0131: nedeni bilinmeyen ate\u015f (NBA), mikrobiyolojik olarak tan\u0131mlanm\u0131\u015f infeksiyon ve klinik olarak tan\u0131mlanm\u0131\u015f infeksiyon. N\u00f6tropeni ba\u015flang\u0131c\u0131nda, ate\u015fin ilk ve \u00fc\u00e7\u00fcnc\u00fc g\u00fcn\u00fc, ate\u015fin d\u00fc\u015ft\u00fc\u011f\u00fc g\u00fcn ya da tedaviye yan\u0131ts\u0131z hastalarda tedavinin 5-7. g\u00fcn\u00fc olmak \u00fczere toplam d\u00f6rt kan \u00f6rne\u011fi al\u0131nd\u0131.<\/p>\n<p> <strong>Bulgular<\/strong>: T\u00fcm ataklarda n\u00f6tropeni ba\u015flang\u0131c\u0131nda PCT d\u00fczeyleri normal de\u011ferlerde bulunurken, CRP d\u00fczeyleri normal de\u011ferlerin \u00fczerinde saptand\u0131. Ate\u015fin \u00fc\u00e7\u00fcnc\u00fc g\u00fcn\u00fc PCT\u2019deki y\u00fcksekli\u011fin tan\u0131mlanm\u0131\u015f infeksiyonu olan gruplarda, NBA grubuna g\u00f6re daha fazla oldu\u011fu g\u00f6zlendi (p&lt;0.05). Sepsisi olan ve olmayan gruplarda PCT d\u00fczeyleri farkl\u0131 bulundu (p&lt;0.001) ve en y\u00fcksek de\u011ferlerine sepsis grubunda ate\u015fin 3. g\u00fcn\u00fcnde ula\u015ft\u0131. Tedaviye yan\u0131ts\u0131z grupta PCT d\u00fczeylerindeki art\u0131\u015f anlaml\u0131 \u00f6l\u00e7\u00fcde s\u00fcrerken, tedaviye yan\u0131t\u0131 olan grupta, ate\u015fin d\u00fc\u015fmesi ile birlikte h\u0131zla normal de\u011ferlere geriledi (p&lt;0.001).\u00a0<\/p>\n<p> <strong>Sonu\u00e7lar<\/strong>: Bu bulgular \u0131\u015f\u0131\u011f\u0131nda, febril n\u00f6tropenik hastalarda PCT\u2019nin, dok\u00fcmante infeksiyonlar\u0131n erken tan\u0131s\u0131nda, infeksiyonun \u015fiddetini ve tedaviye yan\u0131t\u0131 belirlemede yararl\u0131 olaca\u011f\u0131 ve CRP\u2019den daha \u00fcst\u00fcn oldu\u011fu sonucuna var\u0131ld\u0131.\u00a0<\/p>\n","protected":false},"excerpt":{"rendered":"<p>\u00d6zet Ama\u00e7: Maligniteli hastalardaki febril n\u00f6tropeni ataklar\u0131nda prokalsitonin (PCT)\u2019in bakteriyel infeksiyonlar\u0131n tan\u0131sal ve prognostik bir g\u00f6stergesi olarak standard bir parametre olan C-reaktif protein (CRP) ile kar\u015f\u0131la\u015ft\u0131r\u0131l\u0131p de\u011ferlendirilmesi ama\u00e7land\u0131. \u00a0 Y\u00f6ntemler: Kemoterapiye ba\u011fl\u0131 37 hastadaki 40 febril n\u00f6tropenik atak \u00fc\u00e7 gruba ayr\u0131ld\u0131: nedeni bilinmeyen ate\u015f (NBA), mikrobiyolojik olarak tan\u0131mlanm\u0131\u015f infeksiyon ve klinik olarak tan\u0131mlanm\u0131\u015f infeksiyon. N\u00f6tropeni [&hellip;]<\/p>\n","protected":false},"author":0,"featured_media":0,"comment_status":"","ping_status":"","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"footnotes":""},"categories":[5129],"tags":[4061,3604,2654,3369],"class_list":["post-16463","post","type-post","status-publish","format-standard","hentry","category-ozgun-arastirma","tag-bakteriyel-infeksiyonlar","tag-creaktif-protein","tag-febril-notropeni","tag-prokalsitonin"],"acf":[],"_links":{"self":[{"href":"https:\/\/www.klimikdergisi.org\/tr\/wp-json\/wp\/v2\/posts\/16463","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.klimikdergisi.org\/tr\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.klimikdergisi.org\/tr\/wp-json\/wp\/v2\/types\/post"}],"replies":[{"embeddable":true,"href":"https:\/\/www.klimikdergisi.org\/tr\/wp-json\/wp\/v2\/comments?post=16463"}],"version-history":[{"count":0,"href":"https:\/\/www.klimikdergisi.org\/tr\/wp-json\/wp\/v2\/posts\/16463\/revisions"}],"wp:attachment":[{"href":"https:\/\/www.klimikdergisi.org\/tr\/wp-json\/wp\/v2\/media?parent=16463"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.klimikdergisi.org\/tr\/wp-json\/wp\/v2\/categories?post=16463"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.klimikdergisi.org\/tr\/wp-json\/wp\/v2\/tags?post=16463"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}