85 ya\u015f\u0131ndaki kad\u0131n hasta, on g\u00fcn \u00f6nce sol g\u00f6zkapaklar\u0131 ve aln\u0131n sol taraf\u0131nda k\u0131zar\u0131kl\u0131k ve vezik\u00fcler lezyonlar\u0131n geli\u015fmesi \u00fczerine, herpes zoster \u00f6n tan\u0131s\u0131yla Dermatoloji Klini\u011fine yat\u0131r\u0131larak \u0130V olarak asiklovir 3\u00d7500 mg ba\u015flanm\u0131\u015ft\u0131. Bir g\u00fcn sonra diplopi, ajitasyon ve oryantasyon bozuklu\u011fu geli\u015fen hasta, klini\u011fimizle kons\u00fclte edildi. Bilinci kapal\u0131 olan hastan\u0131n y\u00fczde aln\u0131n sol yar\u0131s\u0131nda frontotemporal alana do\u011fru yay\u0131lan ve g\u00f6zkapa\u011f\u0131n\u0131 i\u00e7ine alan hiperemik zeminde yer yer krutlanm\u0131\u015f vezik\u00fcler lezyonlar mevcuttu. Herpes zoster ophthalmicus ve varisella zoster virusu (VZV) ensefaliti \u00f6n tan\u0131s\u0131yla klini\u011fimize nakledilen hastan\u0131n asiklovir dozu 3\u00d7750 mg olarak de\u011fi\u015ftirildi. Beyin-omurilik s\u0131v\u0131s\u0131 (BOS)\u2019nda 150\/mm3 l\u00f6kosit (%90 lenfosit) ve silme eritrosit saptand\u0131. Protein 2149 mg\/dl, glukoz 37 mg\/dl ve e\u015fzamanl\u0131 kan glukozu 72 mg\/dl idi. Gram ve Ehrlich-Ziehl-Neelsen boyamas\u0131nda mikroorganizma g\u00f6r\u00fclmedi. Hastan\u0131n BOS ve kan k\u00fclt\u00fcr\u00fcnde \u00fcreme olmad\u0131. BOS\u2019ta Mycobacterium tuberculosis y\u00f6n\u00fcnden polimeraz zincir reaksiyonu (PZR) ve Brucella standard t\u00fcp agl\u00fctinasyon testi negatifti. Kraniyal manyetik rezonans g\u00f6r\u00fcnt\u00fcleme (MRG)\u2019de, bilateral periventrik\u00fcler beyaz cevherde yayg\u0131n, FLAIR sekanslar\u0131nda hiperintens nod\u00fcler sinyal de\u011fi\u015fiklikleri, kortikal sulkus ve fis\u00fcrlerde derinle\u015fme, bilateral frontal b\u00f6lgelerde 14 mm kal\u0131nl\u0131\u011fa ula\u015fan subdural koleksiyon ve T1 a\u011f\u0131rl\u0131kl\u0131 g\u00f6r\u00fcnt\u00fclerde sa\u011fda 5 mm kal\u0131nl\u0131kta hiperintens akut-subakut hemorajiyi d\u00fc\u015f\u00fcnd\u00fcren de\u011fi\u015fiklikler vard\u0131. Dif\u00fczyon MRG\u2019de beyin sap\u0131, serebellum ve bilateral serebral hemisferlerde sitotoksik \u00f6demle uyumlu dif\u00fczyon k\u0131s\u0131tlamas\u0131 saptanmad\u0131. Beyin ve Sinir Cerrahisi kons\u00fcltasyonunda koleksiyon kortikal atrofiye ba\u011fland\u0131 ve anti\u00f6dem tedavi \u00f6nerildi. Hastaya deksametazon 4\u00d74 mg \u0130V ba\u015fland\u0131; iki g\u00fcnde bir yar\u0131 doza d\u00fc\u015f\u00fcr\u00fclerek 6 g\u00fcn s\u00fcreyle uyguland\u0131. Antiviral tedavisinin 7. g\u00fcn\u00fcnden itibaren hastan\u0131n genel durumu d\u00fczeldi. Bilinci a\u00e7\u0131ld\u0131; kooperasyon ve oryantasyonu d\u00fczeldi ve cilt lezyonlar\u0131 geriledi. BOS’ta PZR ile VZV DNA pozitif olarak saptanan hastan\u0131n asiklovir tedavisi 21 g\u00fcne tamamland\u0131 ve \u015fifayla taburcu edildi.<\/p>\n
\u00d6zet 85 ya\u015f\u0131ndaki kad\u0131n hasta, on g\u00fcn \u00f6nce sol g\u00f6zkapaklar\u0131 ve aln\u0131n sol taraf\u0131nda k\u0131zar\u0131kl\u0131k ve vezik\u00fcler lezyonlar\u0131n geli\u015fmesi \u00fczerine, herpes zoster \u00f6n tan\u0131s\u0131yla Dermatoloji Klini\u011fine yat\u0131r\u0131larak \u0130V olarak asiklovir 3\u00d7500 mg ba\u015flanm\u0131\u015ft\u0131. Bir g\u00fcn sonra diplopi, ajitasyon ve oryantasyon bozuklu\u011fu geli\u015fen hasta, klini\u011fimizle kons\u00fclte edildi. Bilinci kapal\u0131 olan hastan\u0131n y\u00fczde aln\u0131n sol yar\u0131s\u0131nda frontotemporal […]<\/p>\n","protected":false},"author":0,"featured_media":0,"comment_status":"","ping_status":"","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"footnotes":""},"categories":[5131],"tags":[4722,4723,4725],"class_list":["post-14759","post","type-post","status-publish","format-standard","hentry","category-olgu-sunumu","tag-herpes-zoster-ophthalmicus","tag-varisella-zoster-virusu-infeksiyonu","tag-viral-ensefalit"],"acf":[],"_links":{"self":[{"href":"https:\/\/www.klimikdergisi.org\/tr\/wp-json\/wp\/v2\/posts\/14759","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.klimikdergisi.org\/tr\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.klimikdergisi.org\/tr\/wp-json\/wp\/v2\/types\/post"}],"replies":[{"embeddable":true,"href":"https:\/\/www.klimikdergisi.org\/tr\/wp-json\/wp\/v2\/comments?post=14759"}],"version-history":[{"count":0,"href":"https:\/\/www.klimikdergisi.org\/tr\/wp-json\/wp\/v2\/posts\/14759\/revisions"}],"wp:attachment":[{"href":"https:\/\/www.klimikdergisi.org\/tr\/wp-json\/wp\/v2\/media?parent=14759"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.klimikdergisi.org\/tr\/wp-json\/wp\/v2\/categories?post=14759"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.klimikdergisi.org\/tr\/wp-json\/wp\/v2\/tags?post=14759"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}
<\/br> Cite this article as<\/strong>: B\u00fcy\u00fckdemirci A, Y\u00fcksekkaya E, Cesur S, Kaya-K\u0131l\u0131\u00e7 E, Ataman-Hatipo\u011flu \u00c7, K\u0131n\u0131kl\u0131 S. [Encephalitis following herpes zoster ophthalmicus]. Klimik Derg. 2018; 31(2): 157-60. Turkish.<\/p>\n","protected":false},"excerpt":{"rendered":"