Ama\u00e7<\/strong>: Bu \u00e7al\u0131\u015fmada, kemoterapi ba\u015flanacak olan onkoloji hastalar\u0131nda, kemoterapi \u00f6ncesi HBV serolojisinin ara\u015ft\u0131r\u0131l\u0131p ara\u015ft\u0131r\u0131lmad\u0131\u011f\u0131; hepatit B y\u00fczey antijeni (HBsAg) ve\/veya hepatit B kor antikoru (anti-HBc IgG) saptanan olgularda antiviral profilaksi ba\u015flan\u0131p ba\u015flanmad\u0131\u011f\u0131 de\u011ferlendirildi.<\/p>\n \u00d6zet Ama\u00e7: Bu \u00e7al\u0131\u015fmada, kemoterapi ba\u015flanacak olan onkoloji hastalar\u0131nda, kemoterapi \u00f6ncesi HBV serolojisinin ara\u015ft\u0131r\u0131l\u0131p ara\u015ft\u0131r\u0131lmad\u0131\u011f\u0131; hepatit B y\u00fczey antijeni (HBsAg) ve\/veya hepatit B kor antikoru (anti-HBc IgG) saptanan olgularda antiviral profilaksi ba\u015flan\u0131p ba\u015flanmad\u0131\u011f\u0131 de\u011ferlendirildi. Y\u00f6ntemler: \u00c7al\u0131\u015fma May\u0131s 2012- Nisan 2014 tarihleri aras\u0131nda, retrospektif olarak yap\u0131ld\u0131. \u00c7al\u0131\u015fmaya onkoloji poliklini\u011finde tan\u0131 ve tedavi alarak takip edilen ve […]<\/p>\n","protected":false},"author":0,"featured_media":0,"comment_status":"","ping_status":"","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"footnotes":""},"categories":[5129],"tags":[4756,3156,3332],"class_list":["post-14687","post","type-post","status-publish","format-standard","hentry","category-ozgun-arastirma","tag-antineoplastik-protokoller","tag-hepatit-b-virusu","tag-immunosupresyon"],"acf":[],"_links":{"self":[{"href":"https:\/\/www.klimikdergisi.org\/tr\/wp-json\/wp\/v2\/posts\/14687","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.klimikdergisi.org\/tr\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.klimikdergisi.org\/tr\/wp-json\/wp\/v2\/types\/post"}],"replies":[{"embeddable":true,"href":"https:\/\/www.klimikdergisi.org\/tr\/wp-json\/wp\/v2\/comments?post=14687"}],"version-history":[{"count":0,"href":"https:\/\/www.klimikdergisi.org\/tr\/wp-json\/wp\/v2\/posts\/14687\/revisions"}],"wp:attachment":[{"href":"https:\/\/www.klimikdergisi.org\/tr\/wp-json\/wp\/v2\/media?parent=14687"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.klimikdergisi.org\/tr\/wp-json\/wp\/v2\/categories?post=14687"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.klimikdergisi.org\/tr\/wp-json\/wp\/v2\/tags?post=14687"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}
<\/br> Y\u00f6ntemler<\/strong>: \u00c7al\u0131\u015fma May\u0131s 2012- Nisan 2014 tarihleri aras\u0131nda, retrospektif olarak yap\u0131ld\u0131. \u00c7al\u0131\u015fmaya onkoloji poliklini\u011finde tan\u0131 ve tedavi alarak takip edilen ve solid organ malignitesi nedeniyle kemoterapi ba\u015flanan hastalar dahil edildi. \u0130statistiksel de\u011ferlendirme i\u00e7in IBM SPSS Statistics\u00a0 for Windows. Version 22.0 (Statistical Package for the Social Sciences, IBM Corp., Armonk, NY, ABD) program\u0131 kullan\u0131ld\u0131.<\/p>\n
<\/br> Bulgular<\/strong>: \u00c7al\u0131\u015fma sonucunda d\u00fczenli olarak takip edilen 1476 hastan\u0131n verilerine ula\u015f\u0131ld\u0131. Hastalar\u0131n %49.4\u2019\u00fc erkek, %50.6\u2019s\u0131 kad\u0131n olup ortalama ya\u015f 60.6 \u00b113.3 olarak hesapland\u0131. Hastalar\u0131n 864 (%58.1)\u2019\u00fc HBV infeksiyonu a\u00e7\u0131s\u0131ndan taranm\u0131\u015ft\u0131. Tarama i\u00e7in hastalar\u0131n %53.8\u2019inde HBsAg ve anti-HBs birlikte, %4.3\u2019\u00fcnde ise yaln\u0131zca HBsAg kullan\u0131lm\u0131\u015ft\u0131. Anti-HBc IgG hi\u00e7bir hastada ara\u015ft\u0131r\u0131lmam\u0131\u015ft\u0131. Tarama yap\u0131lan hastalar\u0131n %3.5\u2019inde HBsAg pozitifli\u011fi ve %37.9\u2019unda anti-HBs pozitifli\u011fi tespit edilmi\u015fti. HBsAg-pozitif hastalardan %74.1\u2019ine antiviral profilaksi (2 hastada entekavir, 21 hastada lamivudin) ba\u015flanm\u0131\u015f; sekiz hasta ise antiviral profilaksi almam\u0131\u015ft\u0131.<\/p>\n
<\/br> Sonu\u00e7lar<\/strong>: \u00c7al\u0131\u015fma sonucunda kemoterapi alacak hastalar\u0131n \u00e7o\u011funda HBV serolojisi ara\u015ft\u0131r\u0131lm\u0131\u015f olmakla birlikte kullan\u0131lan serolojik parametrelerin, \u00e7o\u011funlukla uygun olmad\u0131\u011f\u0131 saptanm\u0131\u015ft\u0131r. Bu konudaki fark\u0131ndal\u0131\u011f\u0131n art\u0131r\u0131lmas\u0131 i\u00e7in daha fazla \u00e7al\u0131\u015fma gereklidir.\u00a0<\/p>\n
<\/br> Cite this article as<\/strong>: T\u00fcrko\u011flu E, Uysal M, Demirt\u00fcrk N. [Investigation of hepatitis B serology in oncological patients receiving chemotherapy].\u00a0 Klimik Derg. 2018; 31(2): 101-5. Turkish.<\/p>\n","protected":false},"excerpt":{"rendered":"