Agran\u00fclositoz, metimazol ve propiltiourasil gibi antitiroid ila\u00e7lar\u0131n, nadir ancak sonu\u00e7lar\u0131 hayat\u0131 tehdit edebilen bir yan etkisidir. Literat\u00fcrde, \u226540 ya\u015f\u0131nda ve kad\u0131n olmak ve antitiroid ila\u00e7 tedavisinin ilk \u00fc\u00e7 ay\u0131, agran\u00fclositoz geli\u015fimi a\u00e7\u0131s\u0131ndan risk fakt\u00f6r\u00fc olarak g\u00f6sterilmi\u015ftir. Bu yaz\u0131da, belirtilen b\u00fct\u00fcn risk fakt\u00f6rleri bulunan ve metimazolle ili\u015fkili agran\u00fclositoz\/n\u00f6tropeni geli\u015fmi\u015f bir hastada ortaya \u00e7\u0131kan bir yumu\u015fak doku infeksiyonu olgusu, antitiroid ila\u00e7la ili\u015fkili agran\u00fclositoz s\u0131kl\u0131\u011f\u0131, risk fakt\u00f6rleri ve komplikasyonlar\u0131na dikkat \u00e7ekmek amac\u0131yla sunulmu\u015ftur. Hipertiroidi nedeniyle 2.5 ayd\u0131r metimazol kullanan 73 ya\u015f\u0131nda kad\u0131n, ate\u015f, n\u00f6tropeni ve paroni\u015fiyle ba\u015fvurdu. Antitiroid ila\u00e7 ba\u015fland\u0131ktan sonra hemogram takibi yap\u0131lmad\u0131\u011f\u0131 \u00f6\u011frenilen hastaya agran\u00fclositoz\/n\u00f6tropeni tan\u0131s\u0131 konuldu. Hastada iyile\u015fme d\u00f6neminde sol el ba\u015fparmak t\u0131rnak yata\u011f\u0131yla distal falanksta iskemik nekroz ve \u00f6n kolda sel\u00fclit geli\u015fti.\u00a0\u00a0 \u00dc\u00e7 hafta antibiyotik tedavisi ve k\u0131smi parmak amp\u00fctasyonuyla ba\u015far\u0131l\u0131 bir \u015fekilde tedavi edildi. Klimik Dergisi 2018; 31(3): 235-8.<\/p>\n
Cite this article as<\/strong>: Kara\u015fahin \u00d6, \u0130ba-Y\u0131lmaz S. [Soft tissue infection after antithyroid drug-associated agranulocytosis]. Klimik Derg. 2018; 31(3): 235-8. Turkish.<\/p>\n","protected":false},"excerpt":{"rendered":" \u00d6zet Agran\u00fclositoz, metimazol ve propiltiourasil gibi antitiroid ila\u00e7lar\u0131n, nadir ancak sonu\u00e7lar\u0131 hayat\u0131 tehdit edebilen bir yan etkisidir. Literat\u00fcrde, \u226540 ya\u015f\u0131nda ve kad\u0131n olmak ve antitiroid ila\u00e7 tedavisinin ilk \u00fc\u00e7 ay\u0131, agran\u00fclositoz geli\u015fimi a\u00e7\u0131s\u0131ndan risk fakt\u00f6r\u00fc olarak g\u00f6sterilmi\u015ftir. Bu yaz\u0131da, belirtilen b\u00fct\u00fcn risk fakt\u00f6rleri bulunan ve metimazolle ili\u015fkili agran\u00fclositoz\/n\u00f6tropeni geli\u015fmi\u015f bir hastada ortaya \u00e7\u0131kan bir yumu\u015fak […]<\/p>\n","protected":false},"author":0,"featured_media":0,"comment_status":"","ping_status":"","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"footnotes":""},"categories":[5131],"tags":[4780,4778],"class_list":["post-14627","post","type-post","status-publish","format-standard","hentry","category-olgu-sunumu","tag-agranulositoz","tag-metimazol"],"acf":[],"_links":{"self":[{"href":"https:\/\/www.klimikdergisi.org\/tr\/wp-json\/wp\/v2\/posts\/14627","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.klimikdergisi.org\/tr\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.klimikdergisi.org\/tr\/wp-json\/wp\/v2\/types\/post"}],"replies":[{"embeddable":true,"href":"https:\/\/www.klimikdergisi.org\/tr\/wp-json\/wp\/v2\/comments?post=14627"}],"version-history":[{"count":0,"href":"https:\/\/www.klimikdergisi.org\/tr\/wp-json\/wp\/v2\/posts\/14627\/revisions"}],"wp:attachment":[{"href":"https:\/\/www.klimikdergisi.org\/tr\/wp-json\/wp\/v2\/media?parent=14627"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.klimikdergisi.org\/tr\/wp-json\/wp\/v2\/categories?post=14627"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.klimikdergisi.org\/tr\/wp-json\/wp\/v2\/tags?post=14627"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}