Ama\u00e7<\/strong>: Tularemi \u00fclkemizde ilk kez Trakya B\u00f6lgesi\u2019nde tespit edilmi\u015f ve sonraki y\u0131llarda b\u00f6lgede salg\u0131nlar ya\u015fanmaya devam etmi\u015ftir. Etkenin, 2012 y\u0131l\u0131nda Kaynarca deresinin etraf\u0131ndaki farelerde tespit edilmi\u015f olmas\u0131, hastal\u0131\u011f\u0131n bu b\u00f6lge i\u00e7in risk olu\u015fturdu\u011funu g\u00f6stermektedir. Bu \u00e7al\u0131\u015fman\u0131n amac\u0131 Trakya\u2019da riskli bir b\u00f6lgede insanlardaki tularemi insidans\u0131n\u0131 ve dere\/\u015febeke sular\u0131ndaki Francisella tularensis varl\u0131\u011f\u0131n\u0131 ara\u015ft\u0131rmakt\u0131r.<\/p>\n Y\u00f6ntemler<\/strong>: Trakya B\u00f6lgesi\u2019nde riskli b\u00f6lgelerde bulunan 13 k\u00f6y ve bir beldede ya\u015fayan insanlar\u0131n serumunda mikroagl\u00fctinasyon testiyle tularemi seropozitifli\u011fi ara\u015ft\u0131r\u0131ld\u0131. Ocak 2016\u2019da 746 ki\u015fiden al\u0131nan serumlarda seropozitiflik saptanmad\u0131. Ayn\u0131 y\u0131l Aral\u0131k ay\u0131nda bu 746 ki\u015fiden 464\u2019\u00fcne ula\u015f\u0131ld\u0131 ve hi\u00e7birinin serumunda serokonversiyon saptanmad\u0131. Ayr\u0131ca 13 k\u00f6y ve bir beldeden ge\u00e7en derelerden ve \u015febeke sular\u0131ndan al\u0131nan \u00f6rneklerde k\u00fclt\u00fcr ve polimeraz zincir reaksiyonu (PCR) ile F. tularensis varl\u0131\u011f\u0131 ara\u015ft\u0131r\u0131ld\u0131.<\/p>\n Bulgular<\/strong>: Etken k\u00fclt\u00fcrde izole edilemedi; ancak 2 dere ve 3 \u015febeke suyunda PCR ile F. tularensis DNA\u2019s\u0131 tespit edildi. Pozitiflik tespit edilen derelerden biri, Kaynarca deresine \u00e7ok yak\u0131n olan ve ge\u00e7mi\u015f y\u0131llarda vakalar\u0131n g\u00f6r\u00fcld\u00fc\u011f\u00fc Celaliye k\u00f6y\u00fcnden ge\u00e7en dere ve di\u011feri daha uzak mesafede olan, \u015fimdiye kadar tularemi olgusu bildirilmeyen Kavakl\u0131 beldesinden ge\u00e7en deredir. Pozitiflik tespit edilen \u015febeke sular\u0131 Kaynarca deresi etraf\u0131nda bulunan Hamzabey, Ceylank\u00f6y ve Tatark\u00f6y k\u00f6ylerinden al\u0131nan \u015febeke sular\u0131d\u0131r. Pozitiflik saptanan \u015febeke sular\u0131nda, sular\u0131n klorlanmas\u0131 sonras\u0131 molek\u00fcler inceleme tekrarland\u0131 ve tularemi PCR pozitifli\u011fi saptanmad\u0131.<\/p>\n Sonu\u00e7lar<\/strong>: Bu \u00e7al\u0131\u015fmada tularemi insidans\u0131 s\u0131f\u0131r olarak hesaplan\u0131rken, etken sularda tespit edildi. \u0130nsanlarda seropozitiflik saptanmam\u0131\u015f olsa da, 5 su \u00f6rne\u011finde PCR ile etkenin tespit edilmesi zaman zaman etkenlerin su kaynaklar\u0131na ula\u015fabilece\u011fini g\u00f6sterdi. Riskli b\u00f6lgelerde s\u00fcrveyans \u00e7al\u0131\u015fmalar\u0131n\u0131n yap\u0131lmas\u0131n\u0131n salg\u0131nlar\u0131 \u00f6nlemede etkin olabilece\u011fi g\u00f6r\u00fcld\u00fc.\u00a0Klimik Dergisi 2019; 32(1): 78-83.<\/p>\n Cite this article as<\/strong>: U\u011fur M, G\u00fcrcan \u015e, Eskiocak M, Karadenizli A. [Investigation of tularemia incidence and presence of Francisella tularensis in streams\/mains water in a risky region of Thrace]. Klimik Derg. 2019; 32(1): 78-83. Turkish.<\/p>\n","protected":false},"excerpt":{"rendered":" \u00d6zet Ama\u00e7: Tularemi \u00fclkemizde ilk kez Trakya B\u00f6lgesi\u2019nde tespit edilmi\u015f ve sonraki y\u0131llarda b\u00f6lgede salg\u0131nlar ya\u015fanmaya devam etmi\u015ftir. Etkenin, 2012 y\u0131l\u0131nda Kaynarca deresinin etraf\u0131ndaki farelerde tespit edilmi\u015f olmas\u0131, hastal\u0131\u011f\u0131n bu b\u00f6lge i\u00e7in risk olu\u015fturdu\u011funu g\u00f6stermektedir. Bu \u00e7al\u0131\u015fman\u0131n amac\u0131 Trakya\u2019da riskli bir b\u00f6lgede insanlardaki tularemi insidans\u0131n\u0131 ve dere\/\u015febeke sular\u0131ndaki Francisella tularensis varl\u0131\u011f\u0131n\u0131 ara\u015ft\u0131rmakt\u0131r. Y\u00f6ntemler: Trakya B\u00f6lgesi\u2019nde […]<\/p>\n","protected":false},"author":0,"featured_media":0,"comment_status":"","ping_status":"","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"footnotes":""},"categories":[5129],"tags":[4011,3969,4750,3189,3174],"class_list":["post-14489","post","type-post","status-publish","format-standard","hentry","category-ozgun-arastirma","tag-francisella-tularensis","tag-insidans","tag-polimeraz-zincir-reaksiyonu","tag-seroloji","tag-tularemi"],"acf":[],"_links":{"self":[{"href":"https:\/\/www.klimikdergisi.org\/tr\/wp-json\/wp\/v2\/posts\/14489","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.klimikdergisi.org\/tr\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.klimikdergisi.org\/tr\/wp-json\/wp\/v2\/types\/post"}],"replies":[{"embeddable":true,"href":"https:\/\/www.klimikdergisi.org\/tr\/wp-json\/wp\/v2\/comments?post=14489"}],"version-history":[{"count":0,"href":"https:\/\/www.klimikdergisi.org\/tr\/wp-json\/wp\/v2\/posts\/14489\/revisions"}],"wp:attachment":[{"href":"https:\/\/www.klimikdergisi.org\/tr\/wp-json\/wp\/v2\/media?parent=14489"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.klimikdergisi.org\/tr\/wp-json\/wp\/v2\/categories?post=14489"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.klimikdergisi.org\/tr\/wp-json\/wp\/v2\/tags?post=14489"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}