Ba\u011f\u0131\u015f\u0131kl\u0131\u011f\u0131 zay\u0131flam\u0131\u015f hastalar, \u00f6zellikle kanser veya hematolojik malignitesi olanlar ve alojenik kemik ili\u011fi\/hematopoetik k\u00f6k h\u00fccre transplant\u0131 al\u0131c\u0131lar\u0131, hayat\u0131 tehdit edebilen y\u00fcksek bir invazif fungal infeksiyon (\u0130F\u0130) riski alt\u0131ndad\u0131r. Bu hastalarda en s\u0131k \u0130F\u0130 etkenleri Aspergillus ve Candida t\u00fcrleridir. Uzun s\u00fcredir kortikosteroid tedavisi, geni\u015f spektrumlu antimikrobiyal tedavi veya total parenteral n\u00fctrisyon alan hastalar; santral ven\u00f6z kateteri, n\u00f6tropenisi, malignitesi veya yan\u0131klar\u0131 olan hastalar ve d\u00fc\u015f\u00fck do\u011fum a\u011f\u0131rl\u0131kl\u0131 yenido\u011fanlar, \u0130F\u0130 geli\u015fimi a\u00e7\u0131s\u0131ndan en riskli hastalard\u0131r. Antifungal tedaviye erkenden ba\u015flanmas\u0131 zorunludur; ancak \u0130F\u0130\u2019yi klinik bulgulara dayanarak ortaya koymak \u00e7o\u011fu kez m\u00fcmk\u00fcn olmaz. \u0130F\u0130 tedavisinde sistemik antifungal ajanlardan amfoterisin B preparatlar\u0131, flukonazol, vorikonazol, posakonazol, kaspofungin, anidulafungin, mikafungin ve isavukonazol kullan\u0131lmaktad\u0131r. \u0130F\u0130 hastalar\u0131n\u0131n klinik y\u00f6netiminde, lokal epidemiyolojik veriler, antifungal ajanlara kar\u015f\u0131 diren\u00e7 profili ve bunlar\u0131n farmakolojik ve ekonomik y\u00f6nleriyle birlikte klinik deneyimin de \u00f6nemi vard\u0131r. Klimik Dergisi 2019; 32(\u00d6zel Say\u0131 2): 168-73.<\/p>\n
Cite this article as<\/strong>: Tekin S. [Treatment of invasive fungal infections in haematology-oncology patients]. Klimik Derg. 2019; 32(Suppl. 2): 168-73. Turkish.<\/p>\n","protected":false},"excerpt":{"rendered":" Ba\u011f\u0131\u015f\u0131kl\u0131\u011f\u0131 zay\u0131flam\u0131\u015f hastalar, \u00f6zellikle kanser veya hematolojik malignitesi olanlar ve alojenik kemik ili\u011fi\/hematopoetik k\u00f6k h\u00fccre transplant\u0131 al\u0131c\u0131lar\u0131, hayat\u0131 tehdit edebilen y\u00fcksek bir invazif fungal infeksiyon (\u0130F\u0130) riski alt\u0131ndad\u0131r. Bu hastalarda en s\u0131k \u0130F\u0130 etkenleri Aspergillus ve Candida t\u00fcrleridir. Uzun s\u00fcredir kortikosteroid tedavisi, geni\u015f spektrumlu antimikrobiyal tedavi veya total parenteral n\u00fctrisyon alan hastalar; santral ven\u00f6z kateteri, […]<\/p>\n","protected":false},"author":0,"featured_media":0,"comment_status":"","ping_status":"","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"footnotes":""},"categories":[5127],"tags":[3299,4892,4891],"class_list":["post-14303","post","type-post","status-publish","format-standard","hentry","category-derleme","tag-antifungal-ilaclar","tag-hematolojionkoloji-hastalari","tag-invazif-fungal-infeksiyonlar"],"acf":[],"_links":{"self":[{"href":"https:\/\/www.klimikdergisi.org\/tr\/wp-json\/wp\/v2\/posts\/14303","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.klimikdergisi.org\/tr\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.klimikdergisi.org\/tr\/wp-json\/wp\/v2\/types\/post"}],"replies":[{"embeddable":true,"href":"https:\/\/www.klimikdergisi.org\/tr\/wp-json\/wp\/v2\/comments?post=14303"}],"version-history":[{"count":0,"href":"https:\/\/www.klimikdergisi.org\/tr\/wp-json\/wp\/v2\/posts\/14303\/revisions"}],"wp:attachment":[{"href":"https:\/\/www.klimikdergisi.org\/tr\/wp-json\/wp\/v2\/media?parent=14303"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.klimikdergisi.org\/tr\/wp-json\/wp\/v2\/categories?post=14303"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.klimikdergisi.org\/tr\/wp-json\/wp\/v2\/tags?post=14303"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}