K\u0131r\u0131m-Kongo kanamal\u0131 ate\u015fi (KKKA) ve bruselloz \u00fclkemizde yayg\u0131n olarak g\u00f6r\u00fclen zoonotik hastal\u0131klard\u0131r. KKKA ve brusellozun bulgular\u0131 aras\u0131nda ate\u015f, ba\u015f a\u011fr\u0131s\u0131, halsizlik, bulant\u0131, kusma ve ishal yer al\u0131r. KKKA\u2019da cilt, mukoza, organ kanamalar\u0131 ve kreatin kinaz (CK) y\u00fcksekli\u011fi g\u00f6r\u00fclebilir. Her iki hastal\u0131\u011f\u0131n laboratuvar bulgular\u0131 l\u00f6kopeni, trombositopeni, alanin aminotransferaz (ALT), aspartat aminotransferaz (AST), laktat dehidrogenaz (LDH) y\u00fcksekli\u011fi ve aktive parsiyel tromboplastin zaman\u0131 (aPTT) uzamas\u0131d\u0131r. Bu olgu KKKA ve brusellozun kar\u0131\u015fabilece\u011fini ve koinfeksiyonun m\u00fcmk\u00fcn oldu\u011funu vurgulamak amac\u0131yla sunuldu. K\u0131rk alt\u0131 ya\u015f\u0131nda \u00e7obanl\u0131k yapan erkek hastan\u0131n on g\u00fcn \u00f6nce ke\u00e7ilerinden biri \u00f6lm\u00fc\u015f, kesip k\u00f6peklere yem olarak vermi\u015fti. \u00dc\u00e7 g\u00fcn sonra ate\u015f, \u00fc\u015f\u00fcme, titreme, halsizlik \u015fikayetleri ba\u015flam\u0131\u015f; be\u015finci g\u00fcnde 4-5 defa olan sulu, kans\u0131z ishal \u015fikayeti eklenmi\u015fti. Semptomlar\u0131n yedinci g\u00fcn\u00fcnde artan halsizlik, oral al\u0131mda azalma ve uykuya e\u011filim \u015fikayetleriyle hastanemizin acil servisine ba\u015fvuran hasta klini\u011fimize yat\u0131r\u0131ld\u0131. Hastan\u0131n kene tutunma \u00f6yk\u00fcs\u00fc yoktu; ancak KKKA a\u00e7\u0131s\u0131ndan endemik b\u00f6lgede ya\u015f\u0131yordu, genel durumu iyiydi ve ate\u015fi yoktu. Sistem muayeneleri normaldi. Laboratuvar incelemesinde l\u00f6kosit say\u0131s\u0131 3600\/mm3, trombosit say\u0131s\u0131 9000\/mm3, ALT 1871 \u00dc\/lt, AST 7626 \u00dc\/lt, LDH 9283 \u00dc\/lt, CK 516 \u00dc\/lt, aPTT 100.4 saniye, kreatinin (Kr) d\u00fczeyi 1.8 mg\/dl idi. Brucella serum t\u00fcp agl\u00fctinasyon testi 1\/20, Brucella \u201cimmunocapture\u201d agl\u00fctinasyonu 1\/320 titrede pozitifti. KKKA polimeraz zincir reaksiyonu ve KKKA IgM antikorlar\u0131 pozitifti. Hastaya be\u015f g\u00fcn intraven\u00f6z imm\u00fcn globulin verildi; trombosit ve taze donmu\u015f plazma replasman\u0131 yap\u0131ld\u0131. Takiplerde ate\u015f ve kanama bulgusu olmad\u0131; Kr d\u00fczeyleri d\u00fc\u015ft\u00fc. Yat\u0131\u015f\u0131n\u0131n 12. g\u00fcn\u00fcnde taburcu edildi; rifampisin ve doksisiklin tedavisi alt\u0131 haftaya tamamland\u0131. \u00dclkemizin bruselloz ve KKKA a\u00e7\u0131s\u0131ndan endemik bir b\u00f6lge oldu\u011fu g\u00f6z \u00f6n\u00fcne al\u0131nd\u0131\u011f\u0131nda, her iki infeksiyonun ay\u0131r\u0131c\u0131 tan\u0131da akla getirilmesi \u00f6nem ta\u015f\u0131maktad\u0131r. Klimik Dergisi 2019; 32(3): 341-3.<\/p>\n
Cite this article as<\/strong>: Tahmaz A, Deniz M, G\u00fcnay V, \u00d6ztoprak N. [Coinfection of Crimean-Congo haemorrhagic fever and brucellosis: A case report]. Klimik Derg. 2019; 32(3): 341-3. Turkish.<\/p>\n","protected":false},"excerpt":{"rendered":" K\u0131r\u0131m-Kongo kanamal\u0131 ate\u015fi (KKKA) ve bruselloz \u00fclkemizde yayg\u0131n olarak g\u00f6r\u00fclen zoonotik hastal\u0131klard\u0131r. KKKA ve brusellozun bulgular\u0131 aras\u0131nda ate\u015f, ba\u015f a\u011fr\u0131s\u0131, halsizlik, bulant\u0131, kusma ve ishal yer al\u0131r. KKKA\u2019da cilt, mukoza, organ kanamalar\u0131 ve kreatin kinaz (CK) y\u00fcksekli\u011fi g\u00f6r\u00fclebilir. Her iki hastal\u0131\u011f\u0131n laboratuvar bulgular\u0131 l\u00f6kopeni, trombositopeni, alanin aminotransferaz (ALT), aspartat aminotransferaz (AST), laktat dehidrogenaz (LDH) y\u00fcksekli\u011fi […]<\/p>\n","protected":false},"author":0,"featured_media":0,"comment_status":"","ping_status":"","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"footnotes":""},"categories":[5131],"tags":[2821,4013,4078,4330],"class_list":["post-14141","post","type-post","status-publish","format-standard","hentry","category-olgu-sunumu","tag-bruselloz","tag-kirimkongo-kanamali-atesi-virusu","tag-koinfeksiyon","tag-zoonozlar"],"acf":[],"_links":{"self":[{"href":"https:\/\/www.klimikdergisi.org\/tr\/wp-json\/wp\/v2\/posts\/14141","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.klimikdergisi.org\/tr\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.klimikdergisi.org\/tr\/wp-json\/wp\/v2\/types\/post"}],"replies":[{"embeddable":true,"href":"https:\/\/www.klimikdergisi.org\/tr\/wp-json\/wp\/v2\/comments?post=14141"}],"version-history":[{"count":0,"href":"https:\/\/www.klimikdergisi.org\/tr\/wp-json\/wp\/v2\/posts\/14141\/revisions"}],"wp:attachment":[{"href":"https:\/\/www.klimikdergisi.org\/tr\/wp-json\/wp\/v2\/media?parent=14141"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.klimikdergisi.org\/tr\/wp-json\/wp\/v2\/categories?post=14141"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.klimikdergisi.org\/tr\/wp-json\/wp\/v2\/tags?post=14141"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}