Toplum k\u00f6kenli metisiline diren\u00e7li Staphylococcus aureus (TK-MRSA) en \u00e7ok deri ve yumu\u015fak doku infeksiyonlar\u0131 ve nekrotizan pn\u00f6moniye neden olmakla birlikte bir\u00e7ok klinik tabloya da yol a\u00e7abilmektedir. Cilt bariyer b\u00fct\u00fcnl\u00fc\u011f\u00fcn\u00fcn bozulmas\u0131na neden olan travma, damar i\u00e7i ila\u00e7 kullan\u0131m\u0131, cezaevi\/yurt\/bak\u0131mevi gibi kalabal\u0131k ortamlarda bulunma, sosyoekonomik d\u00fczeyin d\u00fc\u015f\u00fck olmas\u0131, nazal S. aureus ta\u015f\u0131y\u0131c\u0131l\u0131\u011f\u0131, ailede sa\u011fl\u0131k \u00e7al\u0131\u015fan\u0131 olmas\u0131, yak\u0131nda antibiyotik kullan\u0131lmas\u0131 ve hastane ba\u015fvurusu \u00f6yk\u00fcs\u00fc, en \u00f6nemli risk fakt\u00f6rleridir. \u00d6zellikle TK-MRSA su\u015flar\u0131nda bulunan Panton-Valentine l\u00f6kosidini (PVL), bir sitotoksin olup l\u00f6kositlerde litik porlar olu\u015fturarak infeksiyonun ciddi seyirli olmas\u0131na neden olmaktad\u0131r. PVL-pozitif su\u015flar\u0131n, doku nekrozu ve apse formasyonuyla ili\u015fkisi saptanm\u0131\u015ft\u0131r. TK-MRSA su\u015flar\u0131 stafilokoksik kromozomal kaset (SCC)mec tip IV veya V gen kaseti i\u00e7erdi\u011finden sadece \u03b2-laktam antibiyotiklere kar\u015f\u0131 diren\u00e7 g\u00f6r\u00fclmektedir. Bu bildiride, TK-MRSA\u2019ya ba\u011fl\u0131 ciddi deri ve yumu\u015fak doku infeksiyonu olan iki olgu sunulmu\u015ftur. TK-MRSA y\u00f6n\u00fcnden risk fakt\u00f6rleri olan olgular\u0131m\u0131z\u0131n her ikisinde de cerrahi olarak apse drenaj\u0131 ve debridman ihtiyac\u0131 olmu\u015ftur. Hastalardan izole edilen MRSA su\u015flar\u0131 SCCmec tip IV ve PVL-pozitif olarak saptanm\u0131\u015ft\u0131r. Genel olarak, toplum k\u00f6kenli deri ve yumu\u015fak doku infeksiyonlar\u0131n\u0131n tedavisinde \u00f6n planda \u03b2-laktam grubu antibiyotikler tercih edilmektedir. TK-MRSA insidans\u0131ndaki art\u0131\u015f g\u00f6z \u00f6n\u00fcnde bulunduruldu\u011funda, ampirik tedavi planlan\u0131rken hastalar TK-MRSA risk fakt\u00f6rleri a\u00e7\u0131s\u0131ndan sorgulanmal\u0131d\u0131r.<\/p>\n
Klimik Dergisi 2020; 33(2): 180-4.<\/p>\n
Cite this article as<\/strong>: Emre A, Seyman D, Merve T\u00fcrker M, et al. [Cases with skin and soft tissue infections caused by community-acquired methicillin-resistant Staphylococcus aureus]. Klimik Derg. 2020; 33(2): 180-4. Turkish.<\/p>\n","protected":false},"excerpt":{"rendered":" Toplum k\u00f6kenli metisiline diren\u00e7li Staphylococcus aureus (TK-MRSA) en \u00e7ok deri ve yumu\u015fak doku infeksiyonlar\u0131 ve nekrotizan pn\u00f6moniye neden olmakla birlikte bir\u00e7ok klinik tabloya da yol a\u00e7abilmektedir. Cilt bariyer b\u00fct\u00fcnl\u00fc\u011f\u00fcn\u00fcn bozulmas\u0131na neden olan travma, damar i\u00e7i ila\u00e7 kullan\u0131m\u0131, cezaevi\/yurt\/bak\u0131mevi gibi kalabal\u0131k ortamlarda bulunma, sosyoekonomik d\u00fczeyin d\u00fc\u015f\u00fck olmas\u0131, nazal S. aureus ta\u015f\u0131y\u0131c\u0131l\u0131\u011f\u0131, ailede sa\u011fl\u0131k \u00e7al\u0131\u015fan\u0131 olmas\u0131, yak\u0131nda […]<\/p>\n","protected":false},"author":0,"featured_media":0,"comment_status":"","ping_status":"","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"footnotes":""},"categories":[5131],"tags":[5034,3647,5036,4246,4580],"class_list":["post-13835","post","type-post","status-publish","format-standard","hentry","category-olgu-sunumu","tag-lokosidinler","tag-metisiline-direncli-staphylococcus-aureus","tag-sccmec-tip-iv","tag-toplum-kokenli-infeksiyonlar","tag-yumusak-doku-infeksiyonlari"],"acf":[],"_links":{"self":[{"href":"https:\/\/www.klimikdergisi.org\/tr\/wp-json\/wp\/v2\/posts\/13835","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.klimikdergisi.org\/tr\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.klimikdergisi.org\/tr\/wp-json\/wp\/v2\/types\/post"}],"replies":[{"embeddable":true,"href":"https:\/\/www.klimikdergisi.org\/tr\/wp-json\/wp\/v2\/comments?post=13835"}],"version-history":[{"count":0,"href":"https:\/\/www.klimikdergisi.org\/tr\/wp-json\/wp\/v2\/posts\/13835\/revisions"}],"wp:attachment":[{"href":"https:\/\/www.klimikdergisi.org\/tr\/wp-json\/wp\/v2\/media?parent=13835"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.klimikdergisi.org\/tr\/wp-json\/wp\/v2\/categories?post=13835"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.klimikdergisi.org\/tr\/wp-json\/wp\/v2\/tags?post=13835"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}