{"id":13691,"date":"2021-01-05T01:21:26","date_gmt":"2021-01-04T22:21:26","guid":{"rendered":"https:\/\/www.klimikdergisi.org\/\/2021\/01\/05\/hacettepe-universitesi-tip-fakultesi-hastanesinde-2017-2019-yillari-arasinda-kan-kulturlerinden-izole-edilen-anaerop-bakteriler-uc-yillik-bir-degerlendirme\/"},"modified":"2021-01-05T01:21:26","modified_gmt":"2021-01-04T22:21:26","slug":"hacettepe-universitesi-tip-fakultesi-hastanesinde-2017-2019-yillari-arasinda-kan-kulturlerinden-izole-edilen-anaerop-bakteriler-uc-yillik-bir-degerlendirme","status":"publish","type":"post","link":"https:\/\/www.klimikdergisi.org\/tr\/2021\/01\/05\/hacettepe-universitesi-tip-fakultesi-hastanesinde-2017-2019-yillari-arasinda-kan-kulturlerinden-izole-edilen-anaerop-bakteriler-uc-yillik-bir-degerlendirme\/","title":{"rendered":"Hacettepe \u00dcniversitesi T\u0131p Fak\u00fcltesi Hastanesi’nde 2017-2019 Y\u0131llar\u0131 Aras\u0131nda Kan K\u00fclt\u00fcrlerinden \u0130zole Edilen Anaerop Bakteriler: \u00dc\u00e7 Y\u0131ll\u0131k Bir De\u011ferlendirme"},"content":{"rendered":"

Ama\u00e7<\/strong>: Anaerop bakteriyemi insidans\u0131 b\u00f6lgeler, sa\u011fl\u0131k kurulu\u015flar\u0131 ve hasta pop\u00fclasyonuna g\u00f6re de\u011fi\u015fkenlik g\u00f6sterir. Kan k\u00fclt\u00fcrlerinden anaerop bakteriler %0.5-13 oran\u0131nda izole edilmektedir. Bu \u00e7al\u0131\u015fman\u0131n amac\u0131 \u00fc\u00e7 y\u0131ll\u0131k bir d\u00f6nemde bir \u00fcniversite hastanesinde anaerop bakteriyemi insidans\u0131n\u0131n ve anaerop bakterilerin da\u011f\u0131l\u0131m\u0131n\u0131n belirlenmesidir.<\/p>\n

Y\u00f6ntemler<\/strong>: Bu \u00e7al\u0131\u015fmada 2017-2019 aras\u0131nda hastanemizde saptanan anaerop bakteriyemi vakalar\u0131n\u0131n mikrobiyolojik ve demografik verileri retrospektif olarak incelenmi\u015ftir. \u0130zolatlar\u0131n tan\u0131mlanmas\u0131nda matriksle desteklenmi\u015f lazer dezorpsiyon iyonizasyon u\u00e7u\u015f zaman\u0131 k\u00fctle spektrometrisi (MALDI-TOF MS) (Bruker Daltonik, Bremen, Almanya) kullan\u0131lm\u0131\u015ft\u0131r.<\/p>\n

Bulgular<\/strong>: Kan k\u00fclt\u00fcrlerinden izole edilen anaerop bakteriler s\u0131ras\u0131yla Bacteroides fragilis grubu (n=40), Cutibacterium spp. (n=27), Gram-pozitif anaerop koklar (n=17), Actinomyces spp. (n=14), Clostridium spp. (n=11), Fusobacterium spp. (n=2), Prevotella spp. (n=2) ve Porphyromonas asaccharolytica (n=1) olarak saptanm\u0131\u015ft\u0131r. Bunlara ek olarak MALDI-TOF MS ile tan\u0131mlanamayan iki Gram-pozitif anaerop basil ve bir Gram-negatif anaerop basil izole edilmi\u015ftir. Polimikrobiyal anaerop bakteriyemi g\u00f6r\u00fclmemi\u015ftir. Hastalar\u0131n %53.8\u2019inin erkek, %46.2\u2019sinin kad\u0131n oldu\u011fu tespit edilmi\u015ftir. Hastalar\u0131n ortanca ya\u015f\u0131n\u0131n 64 (ya\u015f aral\u0131\u011f\u0131 1-92) oldu\u011fu ve %96.6\u2019s\u0131n\u0131n eri\u015fkin hasta oldu\u011fu saptanm\u0131\u015ft\u0131r. Anaerop bakteriyemi geli\u015fen hastalarda komorbiditelerin s\u0131k oldu\u011fu, altta yatan en s\u0131k hastal\u0131\u011f\u0131n ise solid ve hematolojik maligniteler oldu\u011fu belirlenmi\u015ftir. Hastanemizde anaerop bakteriyemi vakalar\u0131nda 30 g\u00fcnl\u00fck mortalite oran\u0131 %25.6 olarak bulunmu\u015ftur. Clostridum spp. ve B. fragilis grubunun mortaliteyle seyreden vakalar\u0131n %73.3\u2019\u00fcn\u00fc olu\u015fturdu\u011fu ve bu iki t\u00fcrde 30 g\u00fcnl\u00fck mortalitenin di\u011fer t\u00fcrlere g\u00f6re anlaml\u0131 oranda y\u00fcksek oldu\u011fu tespit edilmi\u015ftir (p=0.001).<\/p>\n

Sonu\u00e7lar<\/strong>: Sonu\u00e7 olarak anaerop bakteriyemi insidans\u0131 d\u00fc\u015f\u00fck olsa da mortalite oranlar\u0131n\u0131n y\u00fcksek olmas\u0131, uygun antimikrobiyal tedavinin prognoza etkisi ve son y\u0131llarda anaerop bakterilerde direncin gittik\u00e7e artmas\u0131 gibi nedenlerle, sa\u011fl\u0131k kurulu\u015flar\u0131 anaerop bakteriyemi prevalans\u0131n\u0131 ve ili\u015fkili fakt\u00f6rleri d\u00fczenli olarak incelemelidir.\u00a0<\/p>\n

Klimik Dergisi 2020; 33(3): 286-91.<\/p>\n

Cite this article as<\/strong>: Demir-\u00c7uha M, Haz\u0131rolan G. [Anaerobic bacteria isolated from blood cultures in Hacettepe University Faculty of Medicine Hospital between 2017 and 2019: A three-year evaluation]. Klimik Derg. 2020; 33(3): 286-91. Turkish.<\/p>\n","protected":false},"excerpt":{"rendered":"

Ama\u00e7: Anaerop bakteriyemi insidans\u0131 b\u00f6lgeler, sa\u011fl\u0131k kurulu\u015flar\u0131 ve hasta pop\u00fclasyonuna g\u00f6re de\u011fi\u015fkenlik g\u00f6sterir. Kan k\u00fclt\u00fcrlerinden anaerop bakteriler %0.5-13 oran\u0131nda izole edilmektedir. Bu \u00e7al\u0131\u015fman\u0131n amac\u0131 \u00fc\u00e7 y\u0131ll\u0131k bir d\u00f6nemde bir \u00fcniversite hastanesinde anaerop bakteriyemi insidans\u0131n\u0131n ve anaerop bakterilerin da\u011f\u0131l\u0131m\u0131n\u0131n belirlenmesidir. Y\u00f6ntemler: Bu \u00e7al\u0131\u015fmada 2017-2019 aras\u0131nda hastanemizde saptanan anaerop bakteriyemi vakalar\u0131n\u0131n mikrobiyolojik ve demografik verileri retrospektif olarak […]<\/p>\n","protected":false},"author":0,"featured_media":0,"comment_status":"","ping_status":"","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"footnotes":""},"categories":[5129],"tags":[4971,2726,3368],"class_list":["post-13691","post","type-post","status-publish","format-standard","hentry","category-ozgun-arastirma","tag-anaerop-bakteriler","tag-bakteriyemi","tag-kan-kulturu"],"acf":[],"_links":{"self":[{"href":"https:\/\/www.klimikdergisi.org\/tr\/wp-json\/wp\/v2\/posts\/13691","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.klimikdergisi.org\/tr\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.klimikdergisi.org\/tr\/wp-json\/wp\/v2\/types\/post"}],"replies":[{"embeddable":true,"href":"https:\/\/www.klimikdergisi.org\/tr\/wp-json\/wp\/v2\/comments?post=13691"}],"version-history":[{"count":0,"href":"https:\/\/www.klimikdergisi.org\/tr\/wp-json\/wp\/v2\/posts\/13691\/revisions"}],"wp:attachment":[{"href":"https:\/\/www.klimikdergisi.org\/tr\/wp-json\/wp\/v2\/media?parent=13691"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.klimikdergisi.org\/tr\/wp-json\/wp\/v2\/categories?post=13691"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.klimikdergisi.org\/tr\/wp-json\/wp\/v2\/tags?post=13691"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}