ISSN 1301-143X | E-ISSN 1309-1484
Original Article
The First Tularemia Outbreak in the Sivas Province: A Review of 29 Cases
1 Cumhuriyet Üniversitesi, Tıp Fakültesi, İnfeksiyon Hastalıkları ve Klinik Mikrobiyoloji Anabilim Dalı, Sivas, Türkiye  
2 Cumhuriyet Üniversitesi, Tıp Fakültesi, Kulak Burun ve Boğaz Hastalıkları Anabilim Dalı, Sivas, Türkiye  
3 Cumhuriyet Üniversitesi, Tıp Fakültesi, Çocuk Cerrahisi Anabilim Dalı, Sivas, Türkiye  
4 Cumhuriyet Üniversitesi, Tıp Fakültesi, Çocuk Sağlığı ve Hastalıkları Anabilim Dalı, Sivas, Türkiye  
5 Refik Saydam Hıfzıssıhha Merkezi Başkanlığı, Ankara, Türkiye  
Klimik Dergisi 2011; 24: 17-23
DOI: 10.5152/kd.2011.04
Key Words: Tularemia, Sivas.
Abstract

Objective: Several tularemia epidemics have been reported from many provinces in our country in recent years. We report the first tularemia epidemic occurring in Sivas, and some features of the cases. 

 

Methods: Twenty-nine patients admitted to the Infectious Diseases and Clinical Microbiology Clinic of Cumhuriyet University Hospital, between January 2009 and June 2010 were retrospectively investigated. Microagglutination method was used for serological diagnosis. Patients were reviewed and recorded for demographic, clinical and laboratory features.

 

Results: 15 of the patients were male and 14 were female. The  mean age was 41.8 years. The mean time between the onset of the symptoms and diagnosis was 38 days. Francisella tularensis was detected by polymerase chain reaction in lymph node aspirate from two patients. This epidemic was thought to be waterborne. In most of the cases (75.9%), the disease presented itself in the oropharyngeal form. The majority of the patients (93.1%) had cervical lymphadenopathy. Prior to diagnosis of tularemia, several antibiotic regimens ineffective for tularemia were given to 72.4% of the patients. Streptomycin and doxycycline combination was given to most of the patients (44.8%) for treatment. No mortality or sequela except for scar was observed. 

 

Conclusions: Clinicians should be careful for tularemia, even in non-endemic regions. Tularemia should be considered in the differential diagnosis of patients with tonsillopharyngitis and/or cervical lymphadenopathy. 

Key Words
Authors
All
Reviewer's Corner
Author's Corner
Frequently Asked Questions
Survey
AVES | Copyright © 2019 Turkish Society of Clinical Microbiology Infectious Diseases | Latest Update: 30.09.2019