ISSN 1301-143X | E-ISSN 1309-1484
Tularemia: A General Overview on Current Treatment Options
1 Refik Saydam Hıfzıssıhha Merkezi Başkanlığı, Salgın Hastalıklar Araştırma Müdürlüğü, Ankara, Türkiye  
2 Sorgun Devlet Hastanesi, İnfeksiyon Hastalıkları ve Klinik Mikrobiyoloji Kliniği, Yozgat, Türkiye  
Klimik Dergisi 2011; 24: 2-10
DOI: 10.5152/kd.2011.02
Key Words: Tularemia, Francisella tularensis, therapeutics, prophylaxis, guidelines.

Tularemia is a zoonotic infection caused by Francisella tularensis with a worldwide distribution and diverse clinical manifestations. In humans, the disease varies from a localized illness to fulminant, life-threatening pneumonia or septicemia. For decades, streptomycin, gentamicin, and tetracycline have been used for the treatment of tularemia, but more recently, quinolones have been considered as acceptable alternatives. However, there are no randomized trials supporting the use of these antibiotics compared with each other. The increasing number of tularemia outbreaks in regions of Turkey outside the classic endemic areas in recent years has prompted renewed interest in this infectious disease. In this review, suggestions about treatment of tularemia are presented in the light of current literature.

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