In addition to high viral copy number during replication, HBV reverse transciptase also does not have a proofreading function, therefore, many HBV genotypes, subgenotypes, mutants and recombinants can emerge. To date, 10 HBV genotypes (A-J) and almost 40 subgenotypes have been identified. Genotype A is dominant in Northwest Europe, North America and Africa; genotype B and C are common in Asian countries; genotype C is more dominant in East and Southeast Asian countries. Genotype D is widespread in the whole world and is endemic in the Meditteranean area, the Middle East and Western Asia. Genotype E is dominant in Western Africa and genotype H has been found in Central and South America. Genotype G has been reported in France, Germany and America. The genotype H is found in Central America. Recently identified genotype I, a recombination of genotypes A, C and G, was isolated in Vietnam and Laos. The most recent genotype J was identified in the Ryukyu islands in Japan and this genotype has a relationship between gibon\/orangutan genotypes and human genotype C. In this review, HBV genotypes and subgenotypes, their geographic distributions and clinical aspects were overviewed.\u00a0<\/p>\n","protected":false},"excerpt":{"rendered":"
Abstract In addition to high viral copy number during replication, HBV reverse transciptase also does not have a proofreading function, therefore, many HBV genotypes, subgenotypes, mutants and recombinants can emerge. To date, 10 HBV genotypes (A-J) and almost 40 subgenotypes have been identified. Genotype A is dominant in Northwest Europe, North America and Africa; genotype […]<\/p>\n","protected":false},"author":0,"featured_media":0,"comment_status":"","ping_status":"","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"footnotes":""},"categories":[5128],"tags":[4554,3157,4556],"class_list":["post-15246","post","type-post","status-publish","format-standard","hentry","category-review","tag-genotype","tag-hepatitis-b-virus","tag-molecular-epidemiology"],"acf":[],"_links":{"self":[{"href":"https:\/\/www.klimikdergisi.org\/en\/wp-json\/wp\/v2\/posts\/15246","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.klimikdergisi.org\/en\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.klimikdergisi.org\/en\/wp-json\/wp\/v2\/types\/post"}],"replies":[{"embeddable":true,"href":"https:\/\/www.klimikdergisi.org\/en\/wp-json\/wp\/v2\/comments?post=15246"}],"version-history":[{"count":0,"href":"https:\/\/www.klimikdergisi.org\/en\/wp-json\/wp\/v2\/posts\/15246\/revisions"}],"wp:attachment":[{"href":"https:\/\/www.klimikdergisi.org\/en\/wp-json\/wp\/v2\/media?parent=15246"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.klimikdergisi.org\/en\/wp-json\/wp\/v2\/categories?post=15246"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.klimikdergisi.org\/en\/wp-json\/wp\/v2\/tags?post=15246"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}