Objective<\/strong>: The aim of this study is to detect nosocomial infectious agents and their resistance patterns in intensive care unit (ICU) of our hospital and to make a contribution to rational antibiotic usage in the light of these findings.<\/p>\n Methods<\/strong>: 500 patients followed in our ICU between 2015 and 2016 were enrolled in this study. Infectious agents isolated from patients were identified with conventional methods and VITEK\u00ae 2 Compact (bioM\u00e9rieux, Marcy l’Etoile, France) automated system.<\/p>\n Results<\/strong>: In 87 of 500 patients, 105 episodes of nosocomial infections have been identified. Nosocomial infection rate was calculated as 21%. While bloodstream infections (42.8%) were most common in all nosocomial infections, ventilator-associated pneumonia took the first place among device-associated nosocomial infections. 127 microorganisms were detected in patients with diagnosis of nosocomial infections comprising 75 (59%) Gram-negative bacteria, 41 (32.75%) Gram-positive bacteria and 11 (8.66%) yeasts. The most common agents were Acinetobacter spp. (29.9%) and Pseudomonas aeruginosa (19.69%) in Gram-negative bacteria, and Enterococcus spp. (17.32%) and coagulase-negative staphylococci (CoNS) (13.38%) in Gram-positive bacteria. While the most common agents were Acinetobacter spp. (55.5%) in ventilator-associated pneumonia, and Candida spp. (33.3%) and P. aeruginosa (29.6%) in urinary catheter-associated urinary tract infection, Enterococcus gallinarum (31.25%) was observed most commonly in central venous catheter-related bloodstream infections. 17 of 22 enterococcal strains were isolated from blood and 5 were obtained from urine. Resistance to vancomycin and teicoplanin were detected in two urinary E. faecium isolates. Methicillin resistance was identified as 47% in CoNS. Extended-spectrum \u03b2-lactamase positivity was determined in 40% of Escherichia coli strains and 60% of Klebsiella pneumoniae. Carbapenem resistance was observed in 40% of P. aeruginosa, 20% of E. coli and 48.65% of A. baumannii strains. According to the sensitivity results, the most effective antibiotics for Gram-negative bacteria were colistin and aminoglycosides against Acinetobacter spp. and Pseudomonas spp., and carbapenems against E. coli and Klebsiella strains.<\/p>\n Klimik Dergisi 2017; 30(3): 108-13.<\/p>\n Conclusions<\/strong>: Monitoring of nosocomial infections, infectious agents and resistance rates in the ICU has great importance for prevention of infections and rational antibiotic use.<\/p>\n Cite this article as<\/strong>: \u00d6zer-Bal\u0131n \u015e, Akta\u015f-\u015eenol A. [Evaluation of hospital infections in intensive care unit]. Klimik Derg. 2017; 30(3): 108-13. Turkish.<\/p>\n","protected":false},"excerpt":{"rendered":" Abstract Objective: The aim of this study is to detect nosocomial infectious agents and their resistance patterns in intensive care unit (ICU) of our hospital and to make a contribution to rational antibiotic usage in the light of these findings. Methods: 500 patients followed in our ICU between 2015 and 2016 were enrolled in this […]<\/p>\n","protected":false},"author":0,"featured_media":0,"comment_status":"","ping_status":"","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"footnotes":""},"categories":[5130],"tags":[2679,3401,4302,3666],"class_list":["post-14922","post","type-post","status-publish","format-standard","hentry","category-original-article","tag-hospital-infections","tag-intensive-care-units","tag-microbial-drug-resistance","tag-surveillance"],"acf":[],"_links":{"self":[{"href":"https:\/\/www.klimikdergisi.org\/en\/wp-json\/wp\/v2\/posts\/14922","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.klimikdergisi.org\/en\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.klimikdergisi.org\/en\/wp-json\/wp\/v2\/types\/post"}],"replies":[{"embeddable":true,"href":"https:\/\/www.klimikdergisi.org\/en\/wp-json\/wp\/v2\/comments?post=14922"}],"version-history":[{"count":0,"href":"https:\/\/www.klimikdergisi.org\/en\/wp-json\/wp\/v2\/posts\/14922\/revisions"}],"wp:attachment":[{"href":"https:\/\/www.klimikdergisi.org\/en\/wp-json\/wp\/v2\/media?parent=14922"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.klimikdergisi.org\/en\/wp-json\/wp\/v2\/categories?post=14922"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.klimikdergisi.org\/en\/wp-json\/wp\/v2\/tags?post=14922"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}