{"id":14826,"date":"2021-01-05T01:23:00","date_gmt":"2021-01-04T22:23:00","guid":{"rendered":"https:\/\/www.klimikdergisi.org\/\/2021\/01\/05\/detection-of-the-prevalence-of-hbv-hcv-coinfection-in-anti-hcv-positive-samples\/"},"modified":"2021-01-05T01:23:00","modified_gmt":"2021-01-04T22:23:00","slug":"detection-of-the-prevalence-of-hbv-hcv-coinfection-in-anti-hcv-positive-samples","status":"publish","type":"post","link":"https:\/\/www.klimikdergisi.org\/en\/2021\/01\/05\/detection-of-the-prevalence-of-hbv-hcv-coinfection-in-anti-hcv-positive-samples\/","title":{"rendered":"Detection of the Prevalence of HBV\/HCV Coinfection in Anti-HCV-Positive Samples"},"content":{"rendered":"<h1>Abstract<\/h1>\n<p> <strong>Objective:<\/strong> Chronic hepatitis is a common cause of liver-related morbidity due to hepatotropic viruses, such as hepatitis B virus (HBV) and hepatitis C virus (HCV). HBV\/HCV coinfection leads to more severe liver diseases and increased risk of hepatocellular carcinoma. In addition, hepatitis B virus reactivation has been reported after treatment for chronic hepatitis C in patients with HBV\/HCV coinfection. In our study, we aimed to detect the prevalence of HBV\/HCV coinfection in anti-HCV-positive samples, retrospectively.<\/p>\n<p> <strong>Methods:<\/strong> A total of 800 anti-HCV-positive samples were included in the study. Electrochemiluminescence immunoassay for anti-HCV and HBsAg, and quantitative real-time polymerase chain reaction for HBV DNA and HCV RNA were used.<\/p>\n<p> <strong>Results: <\/strong>HBsAg, which indicates HBV infection, was found to be positive in 19 (2.4%) of 800 anti-HCV-positive samples. Out of 19 HBsAg-positive samples, 9 (47%) were simultaneously positive for both HBV DNA and HCV RNA.<\/p>\n<p> <strong>Conclusions<\/strong>: As HBV and HCV share common routes of transmission, coinfections can be encountered. Our results suggest that the prevalence of HBV\/HCV coinfection was not uncommon in anti-HCV-positive samples. Thus, we suggest that patients with chronic HCV infection should also be screened for HBV infection to determine the prognosis and prevent HBV reactivation during antiviral therapy.<\/p>\n<p> <strong>Cite this article as: <\/strong>Fidan I, \u00c7uhadar T, Ko\u00e7 Z, Karaku\u015f R. [Detection of the prevalence of HBV\/HCV coinfection in anti-HCV-positive samples]. Klimik Derg. 2018; 31(1): 16-9. Turkish.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Abstract Objective: Chronic hepatitis is a common cause of liver-related morbidity due to hepatotropic viruses, such as hepatitis B virus (HBV) and hepatitis C virus (HCV). HBV\/HCV coinfection leads to more severe liver diseases and increased risk of hepatocellular carcinoma. In addition, hepatitis B virus reactivation has been reported after treatment for chronic hepatitis C [&hellip;]<\/p>\n","protected":false},"author":0,"featured_media":0,"comment_status":"","ping_status":"","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"footnotes":""},"categories":[5130],"tags":[4079,4033,4035],"class_list":["post-14826","post","type-post","status-publish","format-standard","hentry","category-original-article","tag-coinfection","tag-hepatitis-b-surface-antigens","tag-hepatitis-c-antibodies"],"acf":[],"_links":{"self":[{"href":"https:\/\/www.klimikdergisi.org\/en\/wp-json\/wp\/v2\/posts\/14826","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.klimikdergisi.org\/en\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.klimikdergisi.org\/en\/wp-json\/wp\/v2\/types\/post"}],"replies":[{"embeddable":true,"href":"https:\/\/www.klimikdergisi.org\/en\/wp-json\/wp\/v2\/comments?post=14826"}],"version-history":[{"count":0,"href":"https:\/\/www.klimikdergisi.org\/en\/wp-json\/wp\/v2\/posts\/14826\/revisions"}],"wp:attachment":[{"href":"https:\/\/www.klimikdergisi.org\/en\/wp-json\/wp\/v2\/media?parent=14826"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.klimikdergisi.org\/en\/wp-json\/wp\/v2\/categories?post=14826"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.klimikdergisi.org\/en\/wp-json\/wp\/v2\/tags?post=14826"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}