Agranulocytosis is a rare but life-threating side effect of antithyroid drugs such as methimazole and propylthiouracil. Female gender, age >40 years and first 3 months of antithyroid drug use are shown as risk factors for development of agranulocytosis in the literature. We reported a case of soft tissue infection occurring in a patient who has all above mentioned risk factors and developed agranulocytosis\/neutropenia associated with methimazole in an attempt to notice the frequency of antithyroid drug-associated agranulocytosis, its\u00a0 risk factors and complications. A 73-year-old female using methimazole due to hyperthyroidism for 2.5 months admitted with fever, neutropenia and paronychia. Patient who was not followed hematologically after starting antithyroid drug was diagnosed agranulocytosis\/neutropenia. During her recovery period, an ischemic necrosis in nail bed and distal phalanx of left thumb and a cellulitis on left forearm developed. She was succesfully treated with a 3-week antibiotic therapy and partial thumb amputation. Klimik Dergisi 2018; 31(3): 235-8.<\/p>\n
Cite this article as<\/strong>: Kara\u015fahin \u00d6, \u0130ba-Y\u0131lmaz S. [Soft tissue infection after antithyroid drug-associated agranulocytosis]. Klimik Derg. 2018; 31(3): 235-8. Turkish.<\/p>\n","protected":false},"excerpt":{"rendered":" Abstract Agranulocytosis is a rare but life-threating side effect of antithyroid drugs such as methimazole and propylthiouracil. Female gender, age >40 years and first 3 months of antithyroid drug use are shown as risk factors for development of agranulocytosis in the literature. We reported a case of soft tissue infection occurring in a patient who […]<\/p>\n","protected":false},"author":0,"featured_media":0,"comment_status":"","ping_status":"","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"footnotes":""},"categories":[5132],"tags":[4781,4779],"class_list":["post-14628","post","type-post","status-publish","format-standard","hentry","category-case-report","tag-agranulocytosis","tag-methimazole"],"acf":[],"_links":{"self":[{"href":"https:\/\/www.klimikdergisi.org\/en\/wp-json\/wp\/v2\/posts\/14628","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.klimikdergisi.org\/en\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.klimikdergisi.org\/en\/wp-json\/wp\/v2\/types\/post"}],"replies":[{"embeddable":true,"href":"https:\/\/www.klimikdergisi.org\/en\/wp-json\/wp\/v2\/comments?post=14628"}],"version-history":[{"count":0,"href":"https:\/\/www.klimikdergisi.org\/en\/wp-json\/wp\/v2\/posts\/14628\/revisions"}],"wp:attachment":[{"href":"https:\/\/www.klimikdergisi.org\/en\/wp-json\/wp\/v2\/media?parent=14628"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.klimikdergisi.org\/en\/wp-json\/wp\/v2\/categories?post=14628"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.klimikdergisi.org\/en\/wp-json\/wp\/v2\/tags?post=14628"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}