{"id":14076,"date":"2021-01-05T01:21:57","date_gmt":"2021-01-04T22:21:57","guid":{"rendered":"https:\/\/www.klimikdergisi.org\/\/2021\/01\/05\/cardiovascular-risk-assessment-and-relationship-of-risk-with-triglyceride-high-density-lipoprotein-cholesterol-ratio-in-hiv-infected-patients\/"},"modified":"2021-01-05T01:21:57","modified_gmt":"2021-01-04T22:21:57","slug":"cardiovascular-risk-assessment-and-relationship-of-risk-with-triglyceride-high-density-lipoprotein-cholesterol-ratio-in-hiv-infected-patients","status":"publish","type":"post","link":"https:\/\/www.klimikdergisi.org\/en\/2021\/01\/05\/cardiovascular-risk-assessment-and-relationship-of-risk-with-triglyceride-high-density-lipoprotein-cholesterol-ratio-in-hiv-infected-patients\/","title":{"rendered":"Cardiovascular Risk Assessment and Relationship of Risk With Triglyceride\/High Density Lipoprotein Cholesterol Ratio in HIV-Infected Patients"},"content":{"rendered":"<p><strong>Objective<\/strong>: There isn&#39;t a widely accepted reference method to measure the cardiovascular disease (CVD) risk in human immunodeficiency virus (HIV)-infected patients. In our study, we aimed to investigate the presence of a parameter that would provide insight into CVD risk in HIV-positive individuals and can be conveniently used in their follow-up.<\/p>\n<p><strong>Methods<\/strong>: This retrospective observational study included 160 HIV-infected adults who were followed between 1 January 1996 and 1 June 2017. CVD risk factors and newly developing CVDs during the follow-up of these patients were recorded. By using the Framingham 10-year general CVD risk score (FRS-CVD-10) and American College of Cardiology\/American Heart Association risk estimation (ACC\/AHA CVDRS), patients\u2019 CVD risks at initial and current evaluation were calculated. The association between these calculated values and factors that might be related to CVD risk were investigated.<\/p>\n<p><strong>Results<\/strong>: Of all patients, 82.5% were male and the mean age was 40.06 years. 68.2% of the patients were smokers and 92% had dyslipidemia. It was observed that 25% of the patients who completed the 113-month follow-up developed CVD. 37.1% and 39.4% of the patients were determined to be at high risk in terms of developing CVD according to FRS-CVD-10 and ACC\/AHA CVDRS, respectively. Triglyceride to high density lipoprotein cholesterol ratio (Tg\/HDL-c) was found to be higher in patients who developed CVD during follow-up and in those with high CVD risk scores. The positive predictive value of change in Tg\/HDL-c ratio at the end of the first year in determining the CVD risk was 91.4% when FRS-CVD-10 was accepted as the reference test.<\/p>\n<p><strong>Conclusions<\/strong>: It was concluded that Tg\/HDL-c ratio was a simple, inexpensive and reliable variable which demonstrated the increased risk of CVDs in HIV-infected patients.\u00a0<\/p>\n<p>Klimik Dergisi 2019; 32(3): 285-91.<\/p>\n<p><strong>Cite this article as<\/strong>: G\u00fclten E, Dokuzo\u011fuz B. [Cardiovascular risk assessment and relationship of risk with triglyceride\/high density lipoprotein cholesterol ratio in HIV-infected patients]. Klimik Derg. 2019; 32(3): 285-91. Turkish.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Objective: There isn&#39;t a widely accepted reference method to measure the cardiovascular disease (CVD) risk in human immunodeficiency virus (HIV)-infected patients. In our study, we aimed to investigate the presence of a parameter that would provide insight into CVD risk in HIV-positive individuals and can be conveniently used in their follow-up. Methods: This retrospective observational [&hellip;]<\/p>\n","protected":false},"author":0,"featured_media":0,"comment_status":"","ping_status":"","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"footnotes":""},"categories":[5130],"tags":[4957,3228,4959],"class_list":["post-14076","post","type-post","status-publish","format-standard","hentry","category-original-article","tag-cardiovascular-disease-risk","tag-hiv","tag-trigliserid"],"acf":[],"_links":{"self":[{"href":"https:\/\/www.klimikdergisi.org\/en\/wp-json\/wp\/v2\/posts\/14076","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.klimikdergisi.org\/en\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.klimikdergisi.org\/en\/wp-json\/wp\/v2\/types\/post"}],"replies":[{"embeddable":true,"href":"https:\/\/www.klimikdergisi.org\/en\/wp-json\/wp\/v2\/comments?post=14076"}],"version-history":[{"count":0,"href":"https:\/\/www.klimikdergisi.org\/en\/wp-json\/wp\/v2\/posts\/14076\/revisions"}],"wp:attachment":[{"href":"https:\/\/www.klimikdergisi.org\/en\/wp-json\/wp\/v2\/media?parent=14076"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.klimikdergisi.org\/en\/wp-json\/wp\/v2\/categories?post=14076"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.klimikdergisi.org\/en\/wp-json\/wp\/v2\/tags?post=14076"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}