{"id":13764,"date":"2021-01-05T01:21:32","date_gmt":"2021-01-04T22:21:32","guid":{"rendered":"https:\/\/www.klimikdergisi.org\/\/2021\/01\/05\/clinical-and-laboratory-characteristics-of-covid-19-cases-followed-in-selcuk-university-faculty-of-medicine\/"},"modified":"2021-01-05T01:21:32","modified_gmt":"2021-01-04T22:21:32","slug":"clinical-and-laboratory-characteristics-of-covid-19-cases-followed-in-selcuk-university-faculty-of-medicine","status":"publish","type":"post","link":"https:\/\/www.klimikdergisi.org\/en\/2021\/01\/05\/clinical-and-laboratory-characteristics-of-covid-19-cases-followed-in-selcuk-university-faculty-of-medicine\/","title":{"rendered":"Clinical and Laboratory Characteristics of COVID-19 Cases Followed in Sel\u00e7uk University Faculty of Medicine"},"content":{"rendered":"<p><strong>Objective<\/strong>: Understanding the natural course of COVID-19 and determining its clinical findings are essential for early diagnosis and treatment. In this study, we aimed to investigate clinical and laboratory characteristics of cases followed with a diagnosis of COVID-19 in Sel\u00e7uk University Faculty of Medicine Department of Infectious Diseases and Clinical Microbiology.<\/p>\n<p><strong>Methods<\/strong>: Among patients followed with a diagnosis of possible\/definitive COVID-19, those with a positive SARS-CoV-2 RT-PCR test were evaluated retrospectively in terms of their clin-ical, laboratory and thorax computed tomography (CT) data.<\/p>\n<p><strong>Results<\/strong>: Among 407 patients followed with a diagnosis of possible\/definitive COVID-19, 149 (36.6%) were SARS-CoV-2 RT-PCR test-positive.\u00a0\u00a0 82 (55%) of the patients were female and 67 (45%) were male. Mean age was 49.3\u00b17.6 years. 11 (7.4%) were health care workers. While the most common symptom was cough with 46.3%, fever was observed in 29.5%, sore throat in 27.5% and malaise in 26.8% of the patients. 94 (63.1%) of the patients had underlying diseases. Hypertension and diabetes mellitus were the most common underlying disease. Laboratory findings were\u00a0 leukopenia in 12 (8.1%), lymphopenia in 34 (22.8%), thrombocytopenia in 24 (16.1%), elevated D-dimer levels in 43 (28.9%), elevated lactate dehydrogenase levels in 73 (49%), and elevated C-reactive protein (CRP) levels in 45 (30.2%) patients. While 71 (47.6%) of the patients had normal thorax CT, 43 (28.9%) had mild pneumonia, and 35 (23.5%) moderate pneumonia. D-dimer and CRP levels were higher in those with pneumonia than those without pneumonia (p=0.001 and p=0.001, respectively). As the pneumonia level increased, the increase of D-dimer and CRP levels became evident (p=0.003 and p=0.001, respectively).<\/p>\n<p><strong>Conclusions<\/strong>: The clinical course of COVID-19 patients varies. It is noteworthy that there is a positive correlation between the severity of pneumonia and the increase in D-dimer and CRP levels in COVID-19.<\/p>\n<p>Klimik Dergisi. 2020; 33(2): 122-7.<\/p>\n<p><strong>Cite this article as:<\/strong> S\u00fcmer \u015e, Ural O, Aktu\u011f-Demir N, et al. [Clinical and laboratory characteristics of COVID-19 cases followed in Sel\u00e7uk University Faculty of Medicine]. Klimik Derg. 2020; 33(2): 122-7. Turkish.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Objective: Understanding the natural course of COVID-19 and determining its clinical findings are essential for early diagnosis and treatment. In this study, we aimed to investigate clinical and laboratory characteristics of cases followed with a diagnosis of COVID-19 in Sel\u00e7uk University Faculty of Medicine Department of Infectious Diseases and Clinical Microbiology. Methods: Among patients followed [&hellip;]<\/p>\n","protected":false},"author":0,"featured_media":0,"comment_status":"","ping_status":"","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"footnotes":""},"categories":[5130],"tags":[3460,5019,3491,4230,5020],"class_list":["post-13764","post","type-post","status-publish","format-standard","hentry","category-original-article","tag-clinical-findings","tag-covid19","tag-diagnosis","tag-pandemics","tag-sarscov2"],"acf":[],"_links":{"self":[{"href":"https:\/\/www.klimikdergisi.org\/en\/wp-json\/wp\/v2\/posts\/13764","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.klimikdergisi.org\/en\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.klimikdergisi.org\/en\/wp-json\/wp\/v2\/types\/post"}],"replies":[{"embeddable":true,"href":"https:\/\/www.klimikdergisi.org\/en\/wp-json\/wp\/v2\/comments?post=13764"}],"version-history":[{"count":0,"href":"https:\/\/www.klimikdergisi.org\/en\/wp-json\/wp\/v2\/posts\/13764\/revisions"}],"wp:attachment":[{"href":"https:\/\/www.klimikdergisi.org\/en\/wp-json\/wp\/v2\/media?parent=13764"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.klimikdergisi.org\/en\/wp-json\/wp\/v2\/categories?post=13764"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.klimikdergisi.org\/en\/wp-json\/wp\/v2\/tags?post=13764"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}